病例报告：托洛萨-亨特综合征——是否扩展了视神经脊髓炎谱系障碍的表型？
Case report: Tolosa-Hunt syndrome-expanding the neuromyelitis optica spectrum disorder phenotype?
作者信息
Park Soo-Hyun, Jang Soo-Im, Lee Eun-Ja, Kim Nam-Hee
机构信息
Department of Neurology, Soon Chunhyang University Hospital, Seoul, Republic of Korea.
Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
出版信息
Front Neurol. 2024 Feb 14;15:1326867. doi: 10.3389/fneur.2024.1326867. eCollection 2024.
Abstract
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy caused by the autoantibody of aquaporin-4 (AQP4). Herein, we report a case of Tolosa-Hunt syndrome presenting with abducens palsy and AQP4 antibodies. This was a rare case of AQP4-immunoglobulin G seropositivity in a patient with Tolosa-Hunt syndrome. Our findings may expand the clinical phenotype of NMOSD and indicate that clinicians should consider testing for AQP4 antibodies in patients with Tolosa-Hunt syndrome.
摘要
视神经脊髓炎谱系障碍（NMOSD）是一种由水通道蛋白4（AQP4）自身抗体引起的自身免疫性星形细胞病。在此，我们报告一例表现为外展神经麻痹且伴有AQP4抗体的托洛萨-亨特综合征病例。这是一例托洛萨-亨特综合征患者中罕见的AQP4免疫球蛋白G血清阳性病例。我们的发现可能会扩展NMOSD的临床表型，并表明临床医生应考虑对托洛萨-亨特综合征患者进行AQP4抗体检测。
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