Rougelot Connor, Pippin Micah
Family Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.
Cureus. 2024 Jan 29;16(1):e53174. doi: 10.7759/cureus.53174. eCollection 2024 Jan.
Spontaneous coronary artery dissection (SCAD) is the development of an intramural hematoma that causes a false lumen to form, leading to occlusion and ischemia. It is a rare but separate pathologic cause of acute coronary syndrome, more commonly occurring in females and often associated with underlying vascular conditions. Definitive diagnosis requires invasive coronary angiography. Management is similar to that of myocardial infarction caused by atherosclerosis; however, the majority of SCADs are managed conservatively, as stenting often leads to worse outcomes. Diagnostic and management strategies are primarily based on consensus, with minimal randomized control trials or prospective analyses available to guide patient care.
自发性冠状动脉夹层(SCAD)是指壁内血肿形成,导致假腔形成,进而引起血管闭塞和缺血。它是急性冠状动脉综合征一种罕见但独立的病理原因,更常见于女性,且常与潜在的血管疾病相关。明确诊断需要进行有创冠状动脉血管造影。其治疗方法与动脉粥样硬化所致心肌梗死相似;然而,大多数SCAD患者采用保守治疗,因为支架置入术往往会导致更差的预后。诊断和治疗策略主要基于共识,可供指导患者护理的随机对照试验或前瞻性分析极少。