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阿根廷人类孢子丝菌病病例的基因分型与克隆起源

Genotyping and clonal origin of in human sporotrichosis cases in Argentina.

作者信息

Fernandez Norma B, Spruijtenburg Bram, Tiraboschi Iris N, Meis Jacques F, Lugo Ana, López Joffre María Cecilia, Meijer Eelco F J

机构信息

Sección Micología, División Infectología, Hospital de Clínicas "José de San Martín", Universidad de Buenos Aires, Av. Córdoba 2351, Ciudad Autónoma de Buenos Aires, C1121ABJ, Argentina.

Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, the Netherlands.

出版信息

Med Mycol Case Rep. 2024 Feb 16;43:100633. doi: 10.1016/j.mmcr.2024.100633. eCollection 2024 Mar.

Abstract

is considered a highly virulent emerging pathogen that causes sporotrichosis in humans, mainly after zoonotic transmission from infected cats. The epidemic of this zoonosis that originated from Brazil has spread in the last decades, generating hyperendemic regions in Latin America. We present two cases of human sporotrichosis causes by in Buenos Aires, Argentina, with good clinical response to differing treatments after contact with sick cats. Using Short tandem repeat (STR) genotyping, the two cases appear to be introduced from Brazil and likely originate from the same source.

摘要

被认为是一种高毒力的新兴病原体,主要在通过受感染猫的人畜共患病传播后导致人类孢子丝菌病。这种源自巴西的人畜共患病在过去几十年中已经蔓延,在拉丁美洲产生了高流行区。我们报告了阿根廷布宜诺斯艾利斯两例由 引起的人类孢子丝菌病病例,在接触病猫后,不同治疗方法均产生了良好的临床反应。使用短串联重复序列(STR)基因分型,这两例病例似乎是从巴西传入的,并且可能源自同一来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4026/10899009/7216a088e71e/gr1.jpg

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