Weaver J C
Contemp Issues Clin Biochem. 1985;2:89-107.
The technical outlook is promising for miniature analytical systems which are internally complex but externally simple. Salient features to be anticipated are: The use of miniature electrodes or other sensors in combination with enzymes or immunological compounds for biochemical specificity. The use of arrays of miniature electrodes or other sensors. Relatively low cost because of adaptation of semiconductor fabrication techniques. The attendant possibility of the devices being disposable. The intimate involvement of real time computation. The use of simultaneous replicate assays, with increased confidence in the accuracy of the assay. Overall, rapid assays. Because of these possibilities, it may be concluded that the technological outlook for conducting clinical chemistry assays nearer the patient is promising.
对于内部复杂但外部简单的微型分析系统而言，技术前景十分广阔。值得期待的显著特征包括：将微型电极或其他传感器与酶或免疫化合物结合使用以实现生化特异性；使用微型电极阵列或其他传感器阵列；由于采用了半导体制造技术，成本相对较低；这些设备随之可能具备一次性使用的特性；实时计算的紧密参与；使用同步重复检测，从而提高对检测准确性的信心。总体而言，检测速度快。鉴于这些可能性，可以得出结论，在更靠近患者的位置进行临床化学检测的技术前景十分广阔。
