Pathology Department, APHP Nord, Hopital Saint-Louis, Université Paris Cité, Paris, France.
Pathology Department, APHP Nord, Hopital Saint-Louis, Université Paris Cité, Paris, France; INSERM U976 "Human Immunology, Pathophysiology, and Immunotherapy", Paris, France.
Dermatol Clin. 2024 Apr;42(2):209-217. doi: 10.1016/j.det.2023.08.004. Epub 2023 Sep 11.
In 2005, a new histologic variant of Sweet syndrome (SS) has been described and termed histiocytoid SS (HSS). Clinically, patients had a typical SS, but on skin biopsy, the infiltrates were composed of immature nonblast myeloid cells. Nearly 50% of patients with HSS have myelodysplastic syndrome (MDS). HSS may be the first manifestation leading to the diagnosis of MDS. In 2015, a new category of myeloid dermatosis has been proposed, called myelodysplasia cutis, describing the specific skin infiltration by myelodysplastic cells in patients with MDS.
2005 年，一种新的Sweet 综合征（SS）组织学变异型被描述并命名为组织细胞样 SS（HSS）。临床上，患者具有典型的 SS，但皮肤活检显示浸润物由不成熟的非成髓细胞组成。近 50%的 HSS 患者患有骨髓增生异常综合征（MDS）。HSS 可能是导致 MDS 诊断的首发表现。2015 年，提出了一种新的髓系皮肤病类别，称为骨髓增生异常皮肤，描述了 MDS 患者骨髓增生异常细胞的特定皮肤浸润。
