Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Department of Rehabilitation, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, China.
J Neuroeng Rehabil. 2024 Feb 29;21(1):32. doi: 10.1186/s12984-024-01328-7.
To investigate the resting-state cortical electroencephalogram (EEG) rhythms and networks in patients with chronic stroke and examine their correlation with motor functions of the hemiplegic upper limb.
Resting-state EEG data from 22 chronic stroke patients were compared to EEG data from 19 age-matched and 16 younger-age healthy controls. The EEG rhythmic powers and network metrics were analyzed. Upper limb motor functions were evaluated using the Fugl-Meyer assessment-upper extremity scores and action research arm test.
Compared with healthy controls, patients with chronic stroke showed hemispheric asymmetry, with increased low-frequency activity and decreased high-frequency activity. The ipsilesional hemisphere of stroke patients exhibited reduced alpha and low beta band node strength and clustering coefficient compared to the contralesional side. Low beta power and node strength in the delta band correlated with motor functions of the hemiplegic arm.
The stroke-affected hemisphere showed low-frequency oscillations and decreased influence and functional segregation in the brain network. Low beta activity and redistribution of delta band network between hemispheres were correlated with motor functions of hemiplegic upper limb, suggesting a compensatory mechanism involving both hemispheres post-stroke.
研究慢性脑卒中患者静息态皮质脑电图（EEG）节律和网络，并探讨其与偏瘫上肢运动功能的关系。
将 22 例慢性脑卒中患者的静息态 EEG 数据与 19 例年龄匹配的健康对照者和 16 例年轻健康对照者的 EEG 数据进行比较。分析 EEG 节律功率和网络指标。采用 Fugl-Meyer 上肢评分和动作研究上肢测试评估上肢运动功能。
与健康对照组相比，慢性脑卒中患者表现出半球间不对称，低频活动增加，高频活动减少。与对侧半球相比，脑卒中患者的患侧半球的α和低β频段的节点强度和聚类系数降低。δ频段的低频功率和节点强度与偏瘫上肢的运动功能相关。
脑卒中受累半球表现出低频振荡和脑网络中影响和功能分离的减少。β频段的低频活动和 δ 频段网络在半球间的重新分布与偏瘫上肢的运动功能相关，提示脑卒中后涉及两个半球的代偿机制。
