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儿童焦虑障碍治疗的现状和未来方法。

Current and Future Approaches to Pediatric Anxiety Disorder Treatment.

机构信息

Section on Development and Affective Neuroscience, Emotion and Development Branch, NIMH, Bethesda, Md. (Zugman, Winkler, Qamar, Pine); Division of Human Genetics, School of Medicine, University of Texas Rio Grande Valley, Brownsville (Winkler).

出版信息

Am J Psychiatry. 2024 Mar 1;181(3):189-200. doi: 10.1176/appi.ajp.20231037.

Abstract

This overview critically appraises the literature on the treatment of pediatric anxiety disorders. The two established treatments for these conditions comprise cognitive-behavioral therapy (CBT) and antidepressant medications. Many youths receiving these treatments fail to achieve remission, which creates a need for new treatments. After summarizing the literature on CBT and currently available medications, the authors describe research that lays a foundation for improvements in the treatment of pediatric anxiety disorders. This foundation leverages neuroscientific investigations, also described in the overview, which provide insights on mechanisms of successful treatment.

摘要

本文批判性地评价了儿童焦虑障碍治疗方面的文献。这两种既定的治疗方法包括认知行为疗法(CBT)和抗抑郁药物。许多接受这些治疗的青少年都未能达到缓解,这就需要新的治疗方法。在总结了关于 CBT 和现有药物的文献之后,作者描述了为改善儿童焦虑障碍治疗而奠定基础的研究。该基础利用了神经科学调查,本文也对此进行了描述,这些调查提供了有关成功治疗机制的见解。

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本文引用的文献

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Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2305775120. doi: 10.1073/pnas.2305775120. Epub 2023 Nov 27.
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The role of neurotrophic factors in novel, rapid psychiatric treatments.神经营养因子在新颖、快速的精神科治疗中的作用。
Neuropsychopharmacology. 2024 Jan;49(1):227-245. doi: 10.1038/s41386-023-01717-x. Epub 2023 Sep 6.
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Novel mechanism-based treatments for pediatric anxiety and depressive disorders.基于新型机制的儿童焦虑和抑郁障碍治疗方法。
Neuropsychopharmacology. 2024 Jan;49(1):262-275. doi: 10.1038/s41386-023-01709-x. Epub 2023 Aug 22.

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