Jahangir Majid, Hadi Alireza, Yadegari Zahra, Shahbazi Razieh, Amdjadi Parisa
Department of Prosthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Dental Biomaterials, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dent Res J (Isfahan). 2024 Jan 25;21:4. eCollection 2024.
Polyetheretherketone (PEEK) has favorable properties that make it able to be used as a denture base material, but it is also susceptible to the adhesion of microorganisms. In this study, we applied Octafluoropentyl (meth) acrylate (OFPA) coating on the PEEK polymer surface by using plasma spray and investigated the functional groups present on the surface, changes in the surface energy and adhesion.
In this experimental study, the samples were placed in a control group without surface preparation and three experimental groups that were subjected to plasma spray for 10, 30, and 60 s and then impregnated with degassed Octa fluoropentyl (meth) acrylate (Sigma-Aldrich, USA) monomer. Fourier transform infrared spectroscopy (FTIR) was used to identify the functional groups and new chemical bonds between PEEK and OFPA, and Sessile Drop Method was used to evaluate the surface's wettability. The surface morphology was checked using a LEXT OLS4000 (Olympus-Japan) microscope, and the inhibition of adhesion was also checked by counting the colonies in terms of colony forming unit/mL (CFU/mL). Kurskal-Wallis analysis was conducted to assess adhesion, while wettability was evaluated using analysis of variance and analyses. The level of statistical significance was set at < 0.05.
FTIR analysis confirmed that a chemical between OFPA and PEEK was established. The samples showed a significant increase in the contact angle after 30 s of plasma application (CA = 88.2 ± 7.3). The contact angle decreased again by increasing the surface modification to 60 s (CA = 64.33 ± 5.5). Examining the surface morphology of the samples shows an increase in surface roughness with increasing plasma time up to 60 s. The number of adherent colonies was the lowest in 30 s group, but it was not statistically significant ( = 0.658).
No statistically significant difference in CFU/mL count was found between groups. The contact angle of the 30 s group was significantly higher than the control group.
聚醚醚酮（PEEK）具有良好的性能，使其能够用作义齿基托材料，但它也容易受到微生物的附着。在本研究中，我们通过等离子喷涂在PEEK聚合物表面施加了甲基丙烯酸八氟戊酯（OFPA）涂层，并研究了表面存在的官能团、表面能的变化和附着力。
在本实验研究中，将样品置于未进行表面处理的对照组和三个实验组中，三个实验组分别进行10、30和60秒的等离子喷涂，然后用脱气的甲基丙烯酸八氟戊酯（美国西格玛奥德里奇公司）单体进行浸渍。使用傅里叶变换红外光谱（FTIR）来识别PEEK和OFPA之间的官能团和新化学键，并使用静滴法评估表面的润湿性。使用LEXT OLS4000（日本奥林巴斯）显微镜检查表面形态，还通过以菌落形成单位/毫升（CFU/mL）计数菌落来检查附着力的抑制情况。进行Kruskal-Wallis分析以评估附着力，而使用方差分析和分析来评估润湿性。统计学显著性水平设定为<0.05。
FTIR分析证实了OFPA和PEEK之间建立了化学键。等离子处理30秒后，样品的接触角显著增加（CA = 88.2±7.3）。通过将表面改性增加到60秒，接触角再次降低（CA = 64.33±5.5）。检查样品的表面形态表明，随着等离子处理时间增加到60秒，表面粗糙度增加。30秒组中附着菌落的数量最低，但无统计学显著性（= 0.658）。
各组之间在CFU/mL计数上未发现统计学显著性差异。30秒组的接触角显著高于对照组。
