Patel Dhruv, Bhullar Furqan A, Tagliaferri Ariana R, Melki Gabriel, Grossman Matthew A
Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
Interventional Gastroenterology, St. Joseph's Regional Medical Center, Paterson, USA.
Cureus. 2024 Jan 29;16(1):e53186. doi: 10.7759/cureus.53186. eCollection 2024 Jan.
Pancreatic cancer is one of the most fatal malignancies due to its advanced stages at the time of presentation. Often, it is only diagnosed when patients present with late-stage complications, such as gastric outlet obstruction (GOO). Many patients experience a poor quality of life due to the side effects of GOO, such as persistent nausea, vomiting, and an inability to tolerate an oral diet, and as such, patients deteriorate quickly after their diagnosis. Because pancreatic cancer is diagnosed at advanced stages, many patients are not surgical candidates, and thus treatment is tailored for palliative measures. With GOO specifically, gastrojejunostomy has been the mainstay of palliative management; however, endoscopic stent placement is a new, innovative, and minimally invasive alternative option. Herein, we present a case of GOO as a complication of pancreatic adenocarcinoma, treated with palliative endoscopic stent placement. Further research is warranted to identify patients who would most benefit from this modality of palliation in the treatment of advanced pancreatic cancer.
胰腺癌是最致命的恶性肿瘤之一，因为其在确诊时往往已处于晚期。通常，只有当患者出现晚期并发症，如胃出口梗阻（GOO）时才会被诊断出来。许多患者由于GOO的副作用，如持续恶心、呕吐以及无法耐受经口饮食，导致生活质量较差，因此，患者在确诊后病情迅速恶化。由于胰腺癌在晚期才被诊断出来，许多患者不适合进行手术，因此治疗方案以姑息治疗为主。对于GOO，胃空肠吻合术一直是姑息治疗的主要手段；然而，内镜支架置入是一种新的、创新的、微创的替代选择。在此，我们报告一例因胰腺腺癌并发GOO并接受姑息性内镜支架置入治疗的病例。有必要进行进一步研究，以确定在晚期胰腺癌治疗中最能从这种姑息治疗方式中获益的患者。
