Xu Hualei, Wang Dawei, Cui Kunwei, Wan Ruimei, Chi Quan, Wu Tao
Department of Nuclear Medicine, Taihe County People's Hospital, Taihe, China.
Department of Laboratory Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Radiol Case Rep. 2024 Feb 22;19(5):1851-1854. doi: 10.1016/j.radcr.2024.02.021. eCollection 2024 May.
We presented a case of a 66-year-old female whose initial symptom was headache without obvious inducement. The patient's condition progressed rapidly to a semi-coma state after symptomatic treatment. The F-FDG PET/CT scan revealed circular FDG hypermetabolism and central metabolic defect of the pons and left frontal lobe lesions. The combination of clinical findings, MRI, and Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid led to the diagnosis of Balamuthia mandrillaris encephalitis. The patient died 5 days after discharge.
我们报告了一例66岁女性病例,其初始症状为无明显诱因的头痛。经对症治疗后,患者病情迅速发展至半昏迷状态。F-FDG PET/CT扫描显示脑桥和左侧额叶病变呈圆形FDG高代谢及中央代谢缺损。结合临床表现、MRI以及脑脊液宏基因组下一代测序(NGS)结果,诊断为曼氏巴贝斯虫脑炎。患者出院后5天死亡。