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Pathogens. 2022 Nov 22;11(12):1394. doi: 10.3390/pathogens11121394.
3
Species-Specific Quality Control, Assembly and Contamination Detection in Microbial Isolate Sequences with AQUAMIS.利用 AQUAMIS 对微生物分离物序列进行种特异性质量控制、组装和污染检测。
Genes (Basel). 2021 Apr 26;12(5):644. doi: 10.3390/genes12050644.
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Virulence Factors in Hypervirulent .高毒力菌株中的毒力因子
Front Microbiol. 2021 Apr 8;12:642484. doi: 10.3389/fmicb.2021.642484. eCollection 2021.
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A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae.从全球视角看肺炎克雷伯菌的高毒力与碳青霉烯类耐药性的趋同。
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Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis.在混乱中寻找秩序:肺炎克雷伯菌发病机制中的悬而未决问题。
Infect Immun. 2021 Mar 17;89(4). doi: 10.1128/IAI.00693-20.
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Hypervirulent Klebsiella pneumoniae.高毒力肺炎克雷伯菌。
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KLEB-33的基因组序列草图:一株属于新兴ST16谱系的具有多抗性且能形成聚合生物膜的超毒株,携带多个高毒力基因。

Draft genome sequence of KLEB-33: a convergent biofilm hyperforming multiresistant strain belonging to the emerging ST16 lineage harboring multiple hypervirulence genes.

作者信息

Silva-Bea Sergio, García-Meniño Isidro, Rey Sonia, Romero Manuel, Fernández Javier, Hammerl Jens A, Mora Azucena, Otero Ana

机构信息

Departamento de Microbioloxía e Parasitoloxía, Facultade de Bioloxía, Edificio CIBUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.

Aquatic One Health Research Center (ARCUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.

出版信息

Microbiol Resour Announc. 2024 Apr 11;13(4):e0119223. doi: 10.1128/mra.01192-23. Epub 2024 Mar 1.

DOI:10.1128/mra.01192-23
PMID:38426732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11008166/
Abstract

The emergence of convergent strains showing multiresistance, characteristic of nosocomial pathotypes and hypervirulent traits typical of community-acquired isolates, makes them important models for studying pathogenesis. Here, we describe the convergent, multidrug-resistant KLEB-33 strain harboring several hypervirulence genes and make its genome available to the scientific community.

摘要

出现的具有多重耐药性的趋同菌株,具有医院感染致病型的特征以及社区获得性分离株典型的高毒力特性,使其成为研究发病机制的重要模型。在此,我们描述了携带多个高毒力基因的趋同、多重耐药KLEB-33菌株,并向科学界公开其基因组。