Apollo Hospitals, India.
Apollo Proton Cancer Centre, India.
Indian J Med Microbiol. 2024 Mar-Apr;48:100555. doi: 10.1016/j.ijmmb.2024.100555. Epub 2024 Mar 8.
Meningitis in patients with ventriculo-peritoneal shunt (VP shunt) caused by various species of Candida have been widely described in literature. However, reports describing Candida auris as a cause of meningitis is limited. In this case report we describe a case of multidrug resistant Candida auris meningitis secondary to VP shunt infection successfully treated with intrathecal amphotericin B deoxycholate and intravenous liposomal amphotericin B. This is the second case report of successful treatment of Candida auris meningitis from India. More literature regarding the use of intrathecal/intraventricular echinocandins including optimal dosing and duration of therapy is needed.
已有文献广泛描述了各种念珠菌引起的脑室-腹腔分流（VP 分流）患者的脑膜炎。然而，关于耳念珠菌导致脑膜炎的报告有限。在本病例报告中，我们描述了一例成功治疗 VP 分流感染相关的多重耐药性耳念珠菌脑膜炎的病例，治疗方法为鞘内两性霉素 B 去氧胆酸盐和静脉注射两性霉素 B 脂质体。这是印度第二例成功治疗耳念珠菌脑膜炎的病例报告。需要更多关于鞘内/脑室内棘白菌素类药物的使用（包括最佳剂量和治疗持续时间）的文献。
