Department of Emergency, People's Hospital of Dali Bai Autonomous Prefecture, Dali, Yunnan, China.
Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Medicine (Baltimore). 2024 Mar 1;103(9):e37304. doi: 10.1097/MD.0000000000037304.
Botrychium ternatum ((Thunb.) Sw.), a traditional Chinese medicine, is known for its therapeutic properties in clearing heat, detoxifying, cough suppression, and phlegm elimination. It has been extensively used in clinics for the treatment of many inflammation-related diseases. Currently, there are no documented cases of rhabdomyolysis resulting from Botrychium ternatum intoxication.
A 57-year-old male presented with a complaint of low back discomfort accompanied by tea-colored urine lasting for 4 days. The patient also exhibited markedly increased creatine phosphate kinase and myoglobin levels. Prior to the onset of symptoms, the patient consumed 50 g of Botrychium ternatum to alleviate pharyngodynia.
The patient was diagnosed with rhabdomyolysis due to Botrychium ternatum intoxication.
The patient underwent a substantial volume of fluid resuscitation, diuresis, and alkalization of urine, as well as correction of the acid-base balance and electrolyte disruption.
Following a 10-day treatment plan involving massive fluid resuscitation, diuresis, and alkalization of urine, the patient showed notable improvement in his lower back pain and reported the absence of any discomfort. Following reexamination, the levels of creatine phosphate kinase and myoglobin were restored to within the normal ranges. Additionally, no abnormalities were detected in liver or renal function. As a result, the patient was considered eligible for discharge and was monitored.
Botrychium ternatum intoxication was associated with the development of rhabdomyolysis. To manage this condition, it is recommended that patients provide massive fluid resuscitation, diuresis, alkalization of urine, and other appropriate therapeutic interventions.
Currently, there are no known cases of rhabdomyolysis resulting from Botrychium ternatum intoxication. However, it is important to consider the potential occurrence of rhabdomyolysis resulting from Botrychium ternatum intoxication when there is a correlation between the administration of Botrychium ternatum and the presence of muscular discomfort in the waist or throughout the body, along with tea-colored urine. Considering the levels of creatine phosphate kinase and myoglobin, the diagnosis or exclusion of rhabdomyolysis caused by Botrychium ternatum intoxication should be made, and suitable treatment should be administered accordingly.
卷柏（Botrychium ternatum ((Thunb.) Sw.））作为一种传统中药，以清热、解毒、镇咳、化痰等功效而闻名。它在临床上被广泛用于治疗许多炎症相关疾病。目前，尚无因卷柏中毒导致横纹肌溶解症的报道。
一名 57 岁男性因腰部不适伴茶色尿 4 天就诊。患者还表现出肌酸磷酸激酶和肌红蛋白水平显著升高。在出现症状之前，患者曾服用 50g 卷柏来缓解咽痛。
患者被诊断为卷柏中毒导致的横纹肌溶解症。
患者接受了大量液体复苏、利尿和尿液碱化、酸碱平衡和电解质紊乱的纠正。
经过 10 天的治疗方案，包括大量液体复苏、利尿和尿液碱化，患者的腰痛明显改善，自述无不适。再次检查时，肌酸磷酸激酶和肌红蛋白水平恢复正常。此外，肝肾功能无异常。因此，患者被认为符合出院条件并接受了监测。
卷柏中毒与横纹肌溶解症的发生有关。对于这种情况，建议患者进行大量液体复苏、利尿、尿液碱化等适当的治疗干预。
目前尚无因卷柏中毒导致横纹肌溶解症的报道。然而，当患者服用卷柏并出现腰部或全身肌肉不适，伴有茶色尿时，应考虑卷柏中毒引起横纹肌溶解症的可能性。根据肌酸磷酸激酶和肌红蛋白的水平，应做出由卷柏中毒引起的横纹肌溶解症的诊断或排除，并给予相应的治疗。
