Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway
Department of Mathematics, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
RMD Open. 2024 Mar 1;10(1):e003954. doi: 10.1136/rmdopen-2023-003954.
Cardiovascular (CV) risk factors for rheumatoid arthritis (RA) are conventionally classified as 'traditional' and 'novel'. We argue that this classification is obsolete and potentially counterproductive. Further, we discuss problems with the common practice of adjusting for traditional CV risk factors in statistical analyses. These analyses do not target well-defined effects of RA on CV risk. Ultimately, we propose a future direction for cardiorheumatology research that prioritises optimising current treatments and identifying novel therapeutic targets over further categorisation of well-known risk factors.
心血管 (CV) 风险因素类风湿关节炎 (RA) 通常分为“传统”和“新型”。我们认为这种分类已经过时，并且可能适得其反。此外，我们还讨论了在统计分析中调整传统 CV 风险因素的常见做法所存在的问题。这些分析并不能很好地针对 RA 对 CV 风险的明确影响。最终，我们为心脏风湿病学研究提出了一个未来的方向，即优先优化现有治疗方法，并确定新的治疗靶点，而不是进一步对已知风险因素进行分类。
