Zhang Rui, Pu Weilin, Zhang Xinyuan, Di Ye, Xu Jing, Zhu Meiyan, Tan Yimei, Liu Wei, Krutmann Jean, Wang Jiucun, Ma Yanyun
Human Phenome Institute, Fudan University, Shanghai, China.
Department of Skin and Cosmetic Research, Shanghai Skin Disease Hospital, Shanghai, China.
Photochem Photobiol Sci. 2024 Apr;23(4):711-718. doi: 10.1007/s43630-024-00546-1. Epub 2024 Mar 2.
Previous studies have shown that visible light (VL), especially blue light (BL), could cause significant skin damage. With the emergence of VL protection products, a harmonization of light protection methods has been proposed, but it has not been widely applied in the Chinese population.
Based on this framework, we propose an accurate and simplified method to evaluate the efficacy of BL photoprotection for the Chinese population.
All subjects (n = 30) were irradiated daily using a blue LED light for four consecutive days. Each irradiation dose was 3/4 MPPD (minimum persistent pigmentation darkening). The skin pigmentation parameters, including L, M, and ITA°, were recorded. We proposed the blue light protection factor (BPF) metric based on the skin pigmentation parameters to evaluate the anti-blue light efficacies of different products.
We found that the level of pigmentation rose progressively and linearly as blue light exposure increased. We proposed a metric, BPF, to reflect the anti-blue light efficacy of products based on the linear changes in skin pigment characteristics following daily BL exposure. Moreover, we discovered that the BPF metric could clearly distinguish the anti-blue light efficacies between two products and the control group, suggesting that BPF is an efficient and simple-to-use metric for anti-blue light evaluation.
Our study proposed an accurate and simplified method with an easy-to-use metric, BPF, to accurately characterize the anti-blue light efficacies of cosmetic products, providing support for further development of anti-blue light cosmetics.
先前的研究表明,可见光(VL),尤其是蓝光(BL),会对皮肤造成显著损伤。随着VL防护产品的出现,人们提出了统一的光防护方法,但尚未在中国人群中广泛应用。
基于此框架,我们提出一种准确且简化的方法,用于评估中国人群中蓝光防护的效果。
所有受试者(n = 30)连续四天每天使用蓝色发光二极管灯进行照射。每次照射剂量为3/4最小持续色素沉着变黑(MPPD)。记录皮肤色素沉着参数,包括L、M和ITA°。我们基于皮肤色素沉着参数提出了蓝光防护因子(BPF)指标,以评估不同产品的抗蓝光效果。
我们发现,随着蓝光暴露增加,色素沉着水平呈逐渐上升且呈线性变化。我们提出了BPF指标,以根据每日蓝光暴露后皮肤色素特征的线性变化来反映产品的抗蓝光效果。此外,我们发现BPF指标能够清晰地区分两种产品与对照组之间的抗蓝光效果,这表明BPF是一种用于抗蓝光评估的高效且易于使用的指标。
我们的研究提出了一种准确且简化的方法,以及一个易于使用的指标BPF,以准确表征化妆品的抗蓝光效果,为抗蓝光化妆品的进一步开发提供了支持。