Department of Infection Control and Prevention, Teikyo University Hospital, Japan.
Department of Internal Medicine, Higashi Kawaguchi Hospital, Japan.
Intern Med. 2024 Nov 15;63(22):3101-3104. doi: 10.2169/internalmedicine.3078-23. Epub 2024 Mar 4.
Vibrio fluvialis is a bacterium that can be found in both seawater and freshwater, and it is responsible for causing gastroenteritis and cholangitis. V. fluvialis bacteremia has rarely been reported. We report a case of V. fluvialis bacteremia due to cholangitis in an immunocompetent adult who was exposed to seawater regularly as a sushi chef. The increased risk of V. fluvialis entry into the body resulting from frequent consumption of raw fish and regular exposure to seawater, bile outflow impairment caused by transient inflammation of the bile duct, and the presence of multiple bile acid resistance-related genes in V. fluvialis may lead to the development of acute cholangitis and subsequent bacteremia in immunocompetent patients.
弗氏柠檬酸杆菌是一种存在于海水和淡水中的细菌,可引起肠胃炎和胆管炎。弗氏柠檬酸杆菌菌血症很少见。我们报告了一例因胆管炎导致的弗氏柠檬酸杆菌菌血症的病例,该患者为一名免疫功能正常的成年人,作为寿司厨师经常接触海水。由于频繁食用生鱼和经常接触海水导致弗氏柠檬酸杆菌进入人体的风险增加,胆管炎症导致胆汁流出受损,以及弗氏柠檬酸杆菌中存在多种胆酸耐药相关基因,可能导致免疫功能正常的患者发生急性胆管炎和随后的菌血症。