Uslu Muhammed Fuad, Yilmaz Mustafa, Ateşçelik Metin, Atilgan Feti Ahmet
Muhammed Fuad Uslu, Department of Internal Medicine, Elazig City Hospital, 23100-Elazig, Turkey,
Croat Med J. 2024 Feb 29;65(1):13-19. doi: 10.3325/cmj.2024.65.13.
To evaluate the utility of the systemic immune inflammation index (SII) and systemic inflammation response index (SIRI) in diagnosing pulmonary embolism (PE) in emergency medicine.
We retrospectively reviewed the data of patients who presented to the emergency department and underwent contrast-enhanced computed tomography pulmonary angiography for suspected PE between January 1 and December 31, 2021. In 81/168 patients, the diagnosis of PE was confirmed and in 87/168 it was rejected. The data were analyzed with receiver operating characteristic analysis and binary logistic regression analysis.
Patients with PE had a higher white blood cell count (P<0.001), neutrophils (P=0.002), monocytes (P=0.013), neutrophil/lymphocyte ratio (P<0.001), SII (P<0.001), and SIRI (P<0.001), and a lower lymphocyte count (P=0.002). The SII had a sensitivity of 75.31% and a specificity of 71.26%, while the SIRI had a sensitivity of 82.72% and a specificity of 68.97%. Binary logistic regression analysis showed that the Wells score, D-dimer level, and SII independently influenced the diagnosis of PE.
The SII and SIRI may be used to support the diagnosis of PE in the emergency department.
评估全身免疫炎症指数（SII）和全身炎症反应指数（SIRI）在急诊医学中诊断肺栓塞（PE）的效用。
我们回顾性分析了2021年1月1日至12月31日期间因疑似PE到急诊科就诊并接受对比增强计算机断层扫描肺血管造影的患者数据。168例患者中，81例确诊为PE，87例排除PE。采用受试者工作特征分析和二元逻辑回归分析对数据进行分析。
PE患者的白细胞计数（P<0.001）、中性粒细胞（P=0.002）、单核细胞（P=0.013）、中性粒细胞/淋巴细胞比值（P<0.001）、SII（P<0.001）和SIRI（P<0.001）较高，淋巴细胞计数较低（P=0.002）。SII的敏感性为75.31%，特异性为71.26%；SIRI的敏感性为82.72%，特异性为68.97%。二元逻辑回归分析显示，Wells评分、D-二聚体水平和SII独立影响PE的诊断。
SII和SIRI可用于支持急诊科对PE的诊断。
