[The relationship between birth weight and obstructive sleep apnea in children].

To study the relationship between children's birth weight and obstructive sleep apnea（OSA）. The sleep data and birth information of children who underwent polysomnography in the Department of Otorhinolaryngology-Head and Neck Surgery of Henan Children's Hospital from October 2020 to July 2022 were retrospectively analyzed. The data of OSA detection rate, OSA severity, sleep structure and respiratory parameters in different birth weight groups were analyzed. A total of 2 778 children met the inclusion criteria, including 1 833 males and 945 females. According to birth weight, the selected children were divided into three groups: 122 small for gestational age（SGA） group, 2 313 appropriate for gestational age（AGA）, and 343 large for gestational age（LGA） group. There was no significant difference in age between different groups（=0.061）. In each group, boys are significantly more numerous than girls（=0.001）. The difference in current body mass index（BMI） between groups was statistically significant: the current BMI was higher in the LGA group（17.51±4.01, <0.001）. The severity of OSA was different in different birth weight groups（=0.037）. There was a strong positive correlation between the severity of OSA and birth weight（=0.992）. Children in the SGA group had shorter rapid eye movement（REM） sleep period（19.00[15.18, 23.33], =0.012）, higher obstructive apnea-hypopnea index（OAHI） values（1.75[0.60, 5.13], =0.019）, and had lower central apnea hypopnea index（CAHI） values（0.10[0.00, 0.50], =0.020）. There were no significant differences in sleep structure and respiratory parameters between the LGA group and the AGA group. Multiple regression analysis of the factors affecting the OAHI index showed that the OAHI index of boys was higher than that of girls（95% 1.311-2.096, <0.001）, and age was negatively correlated with the OAHI index（=-0.105, 95% 0.856-0.946, <0.001）, current BMI and OAHI index were positively correlated（=0.037, 95% 1.010-1.065, =0.007）. LGA was positively correlated with OAHI index（=0.346, 95% 1.039-1.921, =0.027）, and the correlation between LGA and OAHI（=0.346） was higher than that between SGA and OAHI（=0.340）. There was no significant difference in the incidence of OSA in children with different birth weight groups, but the OSA severity of LGA group was higher. Gender, age, BMI index and large for gestational age were the influencing factors for the occurrence of OSA in children, which should be paid more attention to in clinical practice.