Xu Wei, Zhu Zheng, Yu Jingxian, Li Juan, Lu Huijuan
School of Nursing, Fudan University, Shanghai, China.
NYU Rory Meyers College of Nursing, New York University, New York, NY, USA.
Asia Pac J Oncol Nurs. 2023 Dec 9;11(3):100361. doi: 10.1016/j.apjon.2023.100361. eCollection 2024 Mar.
This study aimed to establish a symptom network for patients with primary liver cancer posttranscatheter arterial chemoembolization (TACE), identifying core and bridge symptoms. The goal is to provide a foundation for precise and comprehensive nursing interventions.
A total of 1207 post-TACE patients were included using a consecutive sampling method. Data collection involved a general information questionnaire, the Anderson Symptom Assessment Scale, and a primary liver cancer-specific symptom module. The symptom network was constructed using the R language.
In the overall network, distress exhibited the highest strength ( = 1.31) and betweenness ( = 62). Fatigue had the greatest closeness ( = 0.0043), while nausea and vomiting ( = 0.76 ± 0.02) had the highest marginal weights. Nausea had the highest bridge strength ( = 5.263). In the first-time TACE-treated symptom network, sadness ( = 5.673) showed the highest bridge strength, whereas in the non-first-time symptom network, fever ( = 3.061) had the highest bridge strength.
Distress serves as a core symptom, and nausea acts as a bridge symptom after TACE treatment in liver cancer patients. Interventions targeting bridge symptoms should be tailored based on the number of treatments, enhancing the quality of symptom management.
本研究旨在建立经动脉化疗栓塞术（TACE）后原发性肝癌患者的症状网络，识别核心症状和桥梁症状。目标是为精准、全面的护理干预提供基础。
采用连续抽样法纳入1207例TACE术后患者。数据收集包括一般信息问卷、安德森症状评估量表和原发性肝癌特异性症状模块。使用R语言构建症状网络。
在整体网络中，困扰表现出最高的强度（=1.31）和中间中心性（=62）。疲劳具有最大的接近中心性（=0.0043），而恶心和呕吐（=0.76±0.02）具有最高的边际权重。恶心具有最高的桥梁强度（=5.263）。在首次TACE治疗的症状网络中，悲伤（=5.673）显示出最高的桥梁强度，而在非首次症状网络中，发热（=3.061）具有最高的桥梁强度。
困扰是肝癌患者TACE治疗后的核心症状，恶心是桥梁症状。针对桥梁症状的干预应根据治疗次数进行调整，提高症状管理质量。
