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伪装成眼内肿瘤的眼内结核:一例报告。

Intraocular tuberculosis masquerading as ocular tumor: A case report.

作者信息

Abera Michael Teklehaimanot, Fetene Misganaw Badege, Kassa Nibretu Bekele, Yaynishet Yodit Abraham, Tefera Tesfaye Gizaw, Hailu Samuel Sisay

机构信息

Addis Ababa University, College of Health Sciences, Department of Radiology, Addis Ababa, Ethiopia.

出版信息

Radiol Case Rep. 2024 Feb 27;19(5):1949-1955. doi: 10.1016/j.radcr.2024.02.019. eCollection 2024 May.

Abstract

Tuberculosis is one of the most common pediatric problems, especially in the developing world. In spite of that, intraocular tuberculosis is a rare disease that can easily be confused with other noninfectious processes, even in regions where tuberculosis is rampant. Diagnosis is difficult, yet it is very important to provide effective antituberculosis treatment and avoid potentially sight-losing interventions. We present a case of a 2-year-old child with a positive contact history of tuberculosis who presented with progressively worsening seizures and constitutional symptoms for 6 months. Brain computed tomography revealed right frontotemporal region conglomerated ring-enhancing lesions with central necrosis consistent with tuberculosis. On the same scan, a calcified right retinal lesion with a contrast-enhancing soft tissue component was identified. A chest radiograph and abdominal sonography showed evidence of disseminated tuberculosis. Subsequently, antituberculosis treatment was initiated, and the right retinal lesion improved, thus leading to the imaging diagnosis of right intraocular tuberculosis. Early and accurate diagnosis of retinal tuberculosis is of paramount importance in avoiding potentially catastrophic interventions. Neuroimaging is a useful, noninvasive method to consider this difficult diagnosis and also for follow-up.

摘要

结核病是最常见的儿科问题之一,尤其是在发展中世界。尽管如此,眼内结核是一种罕见疾病,即使在结核病猖獗的地区,也很容易与其他非感染性疾病相混淆。诊断困难,但提供有效的抗结核治疗并避免可能导致失明的干预措施非常重要。我们报告一例2岁儿童,有结核病接触史阳性,出现进行性加重的癫痫发作和全身症状6个月。脑部计算机断层扫描显示右额颞叶区域有聚集的环形强化病变,中央坏死,符合结核病表现。在同一次扫描中,发现右视网膜有一个钙化病变,伴有强化的软组织成分。胸部X线片和腹部超声检查显示有播散性结核病的证据。随后开始抗结核治疗,右视网膜病变有所改善,从而得出右眼内结核的影像学诊断。视网膜结核的早期准确诊断对于避免可能带来灾难性后果的干预措施至关重要。神经影像学是一种有用的非侵入性方法,有助于考虑这一疑难诊断并进行随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/087a/10909611/0a76cbb3f2b2/gr1.jpg

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