Salani Ritu, Billingsley Caroline C, Crafton Sarah M
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wexner Medical Center at The Ohio State University Medical Center, Columbus, OH.
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wexner Medical Center at The Ohio State University Medical Center, Columbus, OH.
Am J Obstet Gynecol. 2014 Jul;211(1):7-14. doi: 10.1016/j.ajog.2013.12.002. Epub 2013 Dec 4.
A relatively rare occurrence, pregnancy-associated cancer affects approximately 1 in 1000 pregnancies. Optimizing treatment of the cancer and minimizing harm to the fetus are often dependent on the extent of disease, treatment options required, and the impact on the pregnancy as well as the gestational age of pregnancy. When malignancy is diagnosed, the obstetrician-gynecologist plays a key role in the diagnosis, initial evaluation, and coordination of patient care. Furthermore, the obstetrician-gynecologist may be asked to assist in fertility planning for young women with a new diagnosis of cancer and may be responsible for addressing questions about family-planning needs and the safety of future pregnancy. Therefore, the purpose of this article was to provide the obstetrician-gynecologist with a relevant overview of the current literature regarding concurrent pregnancy and cancer diagnoses, management options, including maternal and neonatal outcomes, as well as the future needs of young women diagnosed with cancer who desire fertility preservation.
妊娠相关癌症相对少见,每1000次妊娠中约有1例受影响。优化癌症治疗并将对胎儿的伤害降至最低通常取决于疾病的程度、所需的治疗方案、对妊娠的影响以及妊娠的孕周。当诊断出恶性肿瘤时,妇产科医生在患者护理的诊断、初步评估和协调中起着关键作用。此外,妇产科医生可能会被要求协助新诊断为癌症的年轻女性进行生育规划,并可能负责解答有关计划生育需求和未来妊娠安全性的问题。因此,本文的目的是为妇产科医生提供有关当前文献的相关概述,内容涉及同时存在妊娠和癌症诊断、管理选项(包括母婴结局)以及希望保留生育能力的癌症确诊年轻女性的未来需求。