Wang Jian-Jun, Huan Yao-Dong, Liu Hua
Department of Otorhinolaryngology, Tangshan Workers Hospital Affiliated to Hebei Medical University, Tangshan City, Hebei Province, China.
Hebei Medical University, Shijiazhuang City, Hbeei Province, China.
Ear Nose Throat J. 2024 Mar 4:1455613241237772. doi: 10.1177/01455613241237772.
Nasopharyngeal melanoma is a rare mucosal malignant melanoma with high recurrence rate, metastasis rate and vascular invasion rate. In this paper, we report a case of primary nasopharyngeal mucosal melanoma. A case of primary nasopharyngeal mucosal melanoma was reported, and its clinical symptoms, pathological characteristics, treatment and follow-up were described in detail. This report describes a 59-year-old male patient with persistent nasal congestion and suspected malignant nasopharyngeal neoplasm. Patients receive surgical resection and adjuvant radiotherapy after complete resection. Imaging studies showed no tissue invasion or lymph node metastases. The results of immunohistochemistry were Melan-A(+), HMB45(+), and S100(+). The final diagnosis was malignant nasopharyngeal melanoma. After 2 years of follow-up, the prognosis was good, and there was no metastasis or recurrence. Nasopharyngeal melanoma is a rare malignancy with a poor prognosis, and surgical resection is the mainstay of treatment. Postoperative adjuvant therapy can improve the rate of local control of lesions. Early diagnosis and thorough examination are extremely important for the patient's prognosis.
鼻咽黑色素瘤是一种罕见的黏膜恶性黑色素瘤，具有高复发率、高转移率和高血管侵袭率。在本文中，我们报告了一例原发性鼻咽黏膜黑色素瘤病例。报告了一例原发性鼻咽黏膜黑色素瘤病例，并详细描述了其临床症状、病理特征、治疗及随访情况。本报告描述了一名59岁男性患者，有持续性鼻塞，怀疑患有鼻咽部恶性肿瘤。患者接受了手术切除，并在完全切除后接受辅助放疗。影像学检查显示无组织侵犯或淋巴结转移。免疫组化结果为Melan - A(+)、HMB45(+)和S100(+)。最终诊断为鼻咽恶性黑色素瘤。经过2年的随访，预后良好，无转移或复发。鼻咽黑色素瘤是一种预后较差的罕见恶性肿瘤，手术切除是主要的治疗方法。术后辅助治疗可提高病变的局部控制率。早期诊断和全面检查对患者的预后极为重要。
