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一项关于更年期女性听力损失的观察性研究。

An Observational Study of Hearing Loss Among Menopausal Women.

作者信息

Namasivaya Navin R B, Prabakaran S, Balaji D, Gowthame K, Rajasekaran S, Sarath Kumar B, Shree Ramya, Lakshana R

机构信息

Department of Otorhinolaryngology (ENT), Chettinad Hospital and Research Institue, Chettinad Academy of Research and Education, Kelambakkam, Tamilnadu 603103 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):176-180. doi: 10.1007/s12070-023-04121-5. Epub 2023 Aug 4.

Abstract

Senile deafness and hearing loss in adults over 50 are major public health issues as a result of the population's ageing demographic. Menopausal women tend to develop hearing loss, while no clear link has been found between the two. The purpose of this study was to determine how menopause and diabetes mellitus affects hearing loss. We assessed 158 menopausal women in total. Pure Tone Audiometry and HbA1c levels was measured, along with appropriate clinical history and examination. The association between those levels and hearing was researched by chi-square test. There were 158 study participants. Mean age of the study population was 50.5 (± 2.49) years. Onset and duration of hard of hearing was assessed in 41 patients (25.9%). 33% (N = 53) of the patients had history of Diabetes mellitus, of which 52.8% offered history of the disease for more than or equal to five years. On audiological assessment, 74.1% had no hearing loss (N = 117), 4.4% had unilateral sensorineural hearing loss (N = 7) and 21.5% had bilateral sensorineural hearing loss (N = 34). Statistics show that hearing loss is statistically connected with ageing and poor glycemic management. With chi square values of 9.629 and P value 0.002 found a significant correlation between ageing and hearing loss. Poor glycemic control is significantly associated with hearing loss with a chi-square value of 4.304 and P value 0.038. Poor glycemic control and menopause is found to be strongly associated with sensorineural hearing loss. Further prospective, hormonal studies including larger population is recommended.

摘要

由于人口老龄化,老年性耳聋和50岁以上成年人的听力损失是主要的公共卫生问题。绝经后女性往往会出现听力损失,但尚未发现两者之间有明确的联系。本研究的目的是确定绝经和糖尿病如何影响听力损失。我们总共评估了158名绝经后女性。测量了纯音听力测定和糖化血红蛋白水平,以及适当的临床病史和检查。通过卡方检验研究了这些水平与听力之间的关联。共有158名研究参与者。研究人群的平均年龄为50.5(±2.49)岁。对41名患者(25.9%)评估了听力减退的发病情况和持续时间。33%(N = 53)的患者有糖尿病史,其中52.8%的患者提供了五年及以上的疾病史。在听力评估中,74.1%的人没有听力损失(N = 117),4.4%的人有单侧感音神经性听力损失(N = 7),21.5%的人有双侧感音神经性听力损失(N = 34)。统计数据表明,听力损失与衰老和血糖管理不佳在统计学上相关。卡方值为9.629,P值为0.002,发现衰老与听力损失之间存在显著相关性。血糖控制不佳与听力损失显著相关,卡方值为4.304,P值为0.038。发现血糖控制不佳和绝经与感音神经性听力损失密切相关。建议进一步进行包括更大规模人群的前瞻性激素研究。

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本文引用的文献

1
Diabetes Mellitus and Hearing Loss: A Complex Relationship.糖尿病与听力损失:复杂的关系。
Medicina (Kaunas). 2023 Jan 30;59(2):269. doi: 10.3390/medicina59020269.
4
Hormones and Hearing: Central Auditory Processing in Women.激素与听力:女性的中枢听觉处理
J Am Acad Audiol. 2019 Jun;30(6):493-501. doi: 10.3766/jaaa.17123. Epub 2018 Sep 25.
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Hearing decline in menopausal women--a 10-year follow-up.
Acta Otolaryngol. 2015 Aug;135(8):807-13. doi: 10.3109/00016489.2015.1023354. Epub 2015 Apr 11.
10
The menopause triggers hearing decline in healthy women.更年期导致健康女性听力下降。
Hear Res. 2010 Jan;259(1-2):31-5. doi: 10.1016/j.heares.2009.09.009. Epub 2009 Sep 23.

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