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围绝经期和绝经后女性的听觉与平衡器官。激素替代疗法对围绝经期和绝经后女性听觉与平衡的影响:当前的知识状况。

Organ of hearing and balance in peri- and postmenopausal women. Effects of hormone replacement therapy on hearing and balance in peri- and post-menopausal women: The current state of knowledge.

作者信息

Orendorz-Frączkowska Krystyna, Temporale Hanna

机构信息

Department and Clinic of Otolaryngology Head and Neck Surgery, Wroclaw Medical University, Poland.

出版信息

Adv Clin Exp Med. 2020 Jun;29(6):751-755. doi: 10.17219/acem/121935.

Abstract

Sensory-neural hearing loss in people over 50 - senile deafness - is currently an increasing problem due to the growing proportion of the elderly people in the population. We can find a number of worldwide publications on hearing loss and dizziness in peri-menopausal women, but the data is inconsistent. Reports describing the influence of sex hormones on the ear and its aging are similarly controversial. This review attempts to summarize the current state of knowledge regarding hearing and balance in women during menopause, based on recent studies in this field. It describes the possible causes of hearing and balance impairment in post-menopausal women other than the mere physiological aging of the ear. The review concludes that impairment of hearing and balance is significantly related to osteoporosis, which results from estrogen deficiency during menopause. It also presents the results of studies on the impact of hormone replacement therapy (HRT) and of particular hormonal components of HRT on hearing and balance. The European population is aging, so accurate knowledge about the effects of HRT on hearing and balance is crucial in the context of improving the quality of life of elderly women through appropriate qualification for hormone substitution therapy. Further detailed and extensive study is necessary to verify the impact of sex hormones on hearing in post-menopausal women, taking into account the type of HRT used, serum hormone levels and the presence or absence of osteoporosis.

摘要

50岁以上人群的感音神经性听力损失——老年性耳聋——目前正成为一个日益严重的问题,这是由于人口中老年人比例不断增加。我们可以找到许多关于围绝经期女性听力损失和头晕的全球出版物,但数据并不一致。描述性激素对耳朵及其衰老影响的报告同样存在争议。本综述试图根据该领域的最新研究,总结有关绝经期间女性听力和平衡的当前知识状态。它描述了绝经后女性听力和平衡受损的可能原因,而不仅仅是耳朵的生理衰老。综述得出结论,听力和平衡受损与骨质疏松症显著相关,骨质疏松症是由绝经期间雌激素缺乏引起的。它还展示了关于激素替代疗法(HRT)以及HRT的特定激素成分对听力和平衡影响的研究结果。欧洲人口正在老龄化,因此在通过适当的激素替代疗法资格认证来提高老年女性生活质量的背景下,准确了解HRT对听力和平衡的影响至关重要。有必要进行进一步详细和广泛的研究,以验证性激素对绝经后女性听力的影响,同时考虑所使用的HRT类型、血清激素水平以及骨质疏松症的存在与否。

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