Department of Otorhinolaryngology, Dumlupinar University, School of Medicine, Kutahya, Turkey.
Am J Otolaryngol. 2012 May-Jun;33(3):322-5. doi: 10.1016/j.amjoto.2011.10.003. Epub 2011 Nov 12.
The aim of this study was to determine the audiologic status and severity of hearing loss in different frequencies between the premenopausal and postmenopausal period in women.
This prospective study involved 28 premenopausal and 27 postmenopausal women. Premenopausal and postmenopausal women were younger than 46 years. Age range for premenopausal and menopause patients was 37 to 46 years. The mean age of menopause women with sensorineural hearing loss in our study was not suitable for the age range of presbyacousis that is commonly seen. Each subject was tested with low- (250-2000 Hz) and high-frequency (4000-8000 Hz) audiometry. For each set of tests, mean values of air conduction at each frequency were calculated for the premenopausal and postmenopausal groups and compared.
The mean ages of the women on premenopausal and postmenopausal groups were 42.0 ± 2.4 and 43.4 ± 2.6 years, respectively. Duration of menopausal period in second group was 2.03 ± 0.85 years. The corresponding mean body mass indexes were 29.7 ± 2.9 and 31.1 ± 3.8 kg/m(2). There was no statistical significance between the 2 groups in mean ages and mean body mass indexes. Hearing thresholds at low and high frequencies were analyzed between the 2 groups in Table 2. At low (250, 500, 1000, and 2000 Hz) and high frequencies (4000, 6000, and 8000 Hz), the mean air-conduction threshold values between the 2 groups were not statistically significant.
Estrogen deficiency may not elevate hearing thresholds in early postmenopausal period; however, further studies of larger series are needed to confirm this.
本研究旨在确定绝经前后女性在不同频率下的听力状况和听力损失程度。
本前瞻性研究共纳入 28 名绝经前和 27 名绝经后女性。绝经前和绝经后女性年龄均小于 46 岁。绝经前和绝经后患者的年龄范围为 37 至 46 岁。我们研究中患有感音神经性听力损失的绝经后女性的平均年龄与常见的老年性聋的年龄范围不相符。每位受试者均接受低频(250-2000 Hz)和高频(4000-8000 Hz)测听。对于每一组测试,计算绝经前和绝经后组在每个频率的气导平均值,并进行比较。
绝经前和绝经后组女性的平均年龄分别为 42.0±2.4 岁和 43.4±2.6 岁。第二组的绝经持续时间为 2.03±0.85 年。相应的平均体重指数分别为 29.7±2.9 和 31.1±3.8 kg/m²。两组的平均年龄和平均体重指数无统计学差异。表 2 分析了两组在低频和高频时的听力阈值。在低频(250、500、1000 和 2000 Hz)和高频(4000、6000 和 8000 Hz)时,两组的气导平均阈值无统计学差异。
雌激素缺乏可能不会导致绝经后早期听力阈值升高;然而,需要进一步的大样本系列研究来证实这一点。