Department of Emergency Medicine, Aksaray University Training and Research Hospital, Aksaray, Turkey.
Department of Cardiology, School of Medicine, Aksaray University, Aksaray, Turkey.
Biomark Med. 2024 Feb;18(3):103-113. doi: 10.2217/bmm-2023-0682. Epub 2024 Mar 5.
The authors investigated the value of novel inflammatory markers, systemic immune-inflammation index and C-reactive protein to albumin ratio (CAR), to predict in-hospital mortality in patients with non-ST elevation myocardial infarction (NSTEMI). A total of 308 patients who underwent percutaneous coronary intervention because of NSTEMI were retrospectively included in the study. Killip classification, Thrombolysis in Myocardial Infarction score, SYNTAX score, and CAR and systemic immune-inflammation index values were calculated. CAR (cutoff: 0.0864; sensitivity: 94.1%; specificity: 40.5%; p = 0.008) and Killip classification (cutoff: 2.5; sensitivity: 64.7%; specificity: 8.9%; p = 0.001) were found to be significantly higher in determining in-hospital mortality. This study revealed that CAR is an inexpensive and significant factor in predicting in-hospital mortality in patients undergoing percutaneous coronary intervention for NSTEMI.
作者研究了新型炎症标志物、全身免疫炎症指数和 C 反应蛋白与白蛋白比值 (CAR) 在预测非 ST 段抬高型心肌梗死 (NSTEMI) 患者住院死亡率方面的价值。 本研究回顾性纳入了 308 例因 NSTEMI 而行经皮冠状动脉介入治疗的患者。计算了 Killip 分级、心肌梗死溶栓 (TIMI) 评分、SYNTAX 评分以及 CAR 和全身免疫炎症指数值。CAR（截断值：0.0864；灵敏度：94.1%；特异性：40.5%；p=0.008）和 Killip 分级（截断值：2.5；灵敏度：64.7%；特异性：8.9%；p=0.001）在确定住院死亡率方面显著更高。本研究表明，CAR 是预测行经皮冠状动脉介入治疗的 NSTEMI 患者住院死亡率的一个经济而重要的因素。
