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中枢神经系统与心血管疾病的对话:联合消灭。

Cross Talks between CNS and CVS Diseases: An Alliance to Annihilate.

机构信息

Department of Pharmacology, Central University of Punjab, Bathinda, Punjab, India.

Department of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab, India.

出版信息

Curr Cardiol Rev. 2024;20(3):63-76. doi: 10.2174/011573403X278550240221112636.

Abstract

Cardiovascular and neurological diseases cause substantial morbidity and mortality globally. Moreover, cardiovascular diseases are the leading cause of death globally. About 17.9 million people are affected by cardiovascular diseases and 6.8 million people die every year due to neurological diseases. The common neurologic manifestations of cardiovascular illness include stroke syndrome which is responsible for unconsciousness and several other morbidities significantly diminished the quality of life of patients. Therefore, it is prudent need to explore the mechanistic and molecular connection between cardiovascular disorders and neurological disorders. The present review emphasizes the association between cardiovascular and neurological diseases specifically Parkinson's disease, Alzheimer's disease, and Huntington's disease.

摘要

心血管和神经疾病在全球范围内导致了大量的发病率和死亡率。此外,心血管疾病是全球范围内的主要死因。约有 1790 万人受到心血管疾病的影响,每年有 680 万人因神经疾病而死亡。心血管疾病的常见神经表现包括中风综合征,其可导致昏迷和其他几种严重降低患者生活质量的疾病。因此,有必要探索心血管疾病和神经疾病之间的机制和分子联系。本综述强调了心血管疾病和神经疾病之间的关联,特别是帕金森病、阿尔茨海默病和亨廷顿病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2207/11284694/13e6cd925cbb/CCR-20-E040324227603_F1.jpg

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