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肾盂肾炎患者的 Wunderlich 综合征。

Wunderlich syndrome in a patient with pyelonephritis.

机构信息

Department of Internal Medicine, Singapore General Hospital, Singapore

Department of Internal Medicine, Singapore General Hospital, Singapore.

出版信息

BMJ Case Rep. 2024 Mar 5;17(3):e257325. doi: 10.1136/bcr-2023-257325.

Abstract

An elderly female patient with left pyelonephritis developed worsening left flank pain, hypotension and a drop in haemoglobin (Hb) from 97 g/L to 67g/L on the third day of her admission. There was no recent trauma, history of coagulopathy or risk factors for renal malignancy or vascular disease.A contrasted CT scan of the kidneys revealed a 3.8 cm left renal subcapsular haematoma with no active contrast extravasation. Her atraumatic subcapsular haematoma fulfils two out of three clinical features of Lenk's triad (acute flank pain, hypovolaemic shock), suggestive of Wunderlich syndrome. Urine and blood cultures grew and she was managed conservatively with culture-directed antibiotics, fluids and blood products.Wunderlich syndrome is a rare complication of pyelonephritis and should be considered in patients with pyelonephritis who develop acute severe flank pain, Hb drop and haemodynamic instability. Appropriate medical and surgical therapies need to be instituted early to ensure good outcomes.

摘要

一位老年女性患者因左侧肾盂肾炎入院,在入院第三天出现左侧腰痛加剧、低血压和血红蛋白(Hb)从 97g/L 降至 67g/L。患者无近期外伤史、凝血功能障碍史或肾恶性肿瘤或血管疾病的危险因素。肾脏对比 CT 扫描显示 3.8cm 大小的左肾包膜下血肿,无活动性对比外渗。她的非创伤性包膜下血肿符合 Lenk 三联征的两个临床特征(急性腰痛、低血容量性休克),提示 Wunderlich 综合征。尿液和血液培养均阳性,她接受了针对培养物的抗生素、液体和血制品的保守治疗。Wunderlich 综合征是肾盂肾炎的罕见并发症,对于发生急性严重腰痛、Hb 下降和血液动力学不稳定的肾盂肾炎患者,应考虑该病。需要尽早采取适当的医疗和手术治疗,以确保良好的治疗效果。

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