Internal Medicine, Hospital Universiti Sains Malaysia, Kota Bahru, Kelantan, Malaysia
Universiti Sains Malaysia - Kampus Kesihatan, Kota Bharu, Kelantan, Malaysia.
BMJ Case Rep. 2024 Mar 5;17(3):e258215. doi: 10.1136/bcr-2023-258215.
We report a case of Raynaud's phenomenon in a patient with psoriatic arthritis (PsA). A middle-aged right-handed housewife presented with complaints of severely painful hand discolouration for 1 week, which usually worsened with cold exposure. She was diagnosed with PsA 6 months earlier. Her PsA was well controlled with weekly methotrexate. Physical examination showed no features of scleroderma or skin necrosis of her right hand. Both radial pulses were strong and symmetrical. Her nailfolds were visibly normal. The extractable nuclear antigen panel and other blood investigations were negative for scleroderma and other possible causes of secondary Raynaud's phenomenon. Occupational or environmental factors were also excluded. Dermatoscope examination of the nailfolds revealed some areas of dilated capillary loops, areas of vascular sparing and proximal nail fold telangiectasia. The diagnosis of secondary Raynaud's phenomenon was made, and an oral calcium channel blocker was started. The patient had significant improvement in symptoms shortly afterwards.
我们报告一例伴有银屑病关节炎(PsA)的雷诺现象患者。一名中年右利手家庭主妇因右手严重疼痛变色 1 周而就诊,这种情况通常在接触寒冷时会加重。她在 6 个月前被诊断为 PsA。她的 PsA 使用每周一次甲氨蝶呤治疗得到了很好的控制。体格检查未发现硬皮病或右手皮肤坏死的特征。桡动脉搏动均强劲且对称。甲襞可见正常。针对硬皮病和其他可能引起继发性雷诺现象的原因的可提取核抗原谱和其他血液检查均为阴性。也排除了职业或环境因素。甲襞的皮肤镜检查显示一些区域的毛细血管环扩张,一些区域的血管保存和近端甲襞毛细血管扩张。诊断为继发性雷诺现象,并开始口服钙通道阻滞剂。此后不久,患者的症状有了显著改善。