Department of Neurosurgery, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Department of Radiology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
BMC Musculoskelet Disord. 2024 Mar 6;25(1):200. doi: 10.1186/s12891-024-07324-1.
The assessment of bone density has gained significance in recent years due to the aging population. Accurate assessment of bone density is crucial when deciding on the appropriate treatment plan for spinal stabilization surgery. The objective of this work was to determine the trabecular bone density values of the subaxial cervical, thoracic and lumbar spine using Hounsfield units.
Data from 200 patients who underwent contrast-enhanced polytrauma computed tomography at a maximum care hospital over a two-year period were retrospectively analyzed. HUs were measured with an elliptical measurement field in three different locations within the vertebral body: below the upper plate, in the middle of the vertebral body, and above the base plate. The measured Hounsfield units were converted into bone density values using a validated formula.
The mean age of the patient collective was 47.05 years. Mean spinal bone density values decreased from cranial to caudal (C3: 231.79 mg/cm; L5: 155.13 mg/cm; p < 0.001), with the highest values in the upper cervical spine. Bone density values generally decreased with age in all spinal segments. There was a clear decrease in values after age 50 years (p < 0.001).
In our study, bone density decreased from cranial to caudal with higher values in the cervical spine. These data from the individual spinal segments may be helpful to comprehensively evaluate the status of the spine and to design a better preoperative plan before instrumentation.
由于人口老龄化,近年来骨密度评估变得越来越重要。准确评估骨密度对于决定脊柱稳定手术的适当治疗方案至关重要。本研究的目的是使用亨氏单位(Hounsfield units)确定下颈椎、胸椎和腰椎的小梁骨密度值。
回顾性分析了 200 名在一家最高级护理医院接受增强型多发伤计算机断层扫描(CT)的患者的数据。在椎体的三个不同位置(上板下方、椎体中部和基板上方)用椭圆形测量区域测量 HUs。使用经过验证的公式将测量的 Hounsfield 单位转换为骨密度值。
患者群体的平均年龄为 47.05 岁。脊柱骨密度值从颅侧到尾侧逐渐降低(C3:231.79mg/cm;L5:155.13mg/cm;p<0.001),颈椎上段的骨密度值最高。所有脊柱节段的骨密度值均随年龄增长而降低,50 岁后明显降低(p<0.001)。
在我们的研究中,骨密度从颅侧到尾侧逐渐降低,颈椎上段的骨密度值较高。这些来自各个脊柱节段的数据可能有助于全面评估脊柱状况,并在器械置入术前制定更好的术前计划。