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评估具有小转弯半径的带弹簧可控针周围的组织损伤。

Assessing Tissue Damage Around a Tape Spring Steerable Needle With Sharp Turn Radii.

作者信息

Abdoun Omar T, Yim Mark

机构信息

Department of Bioengineering and The Perelman School of MedicineUniversity of Pennsylvania Philadelphia PA 19104 USA.

Department of Mechanical Engineering and Applied MechanicsUniversity of Pennsylvania Philadelphia PA 19104 USA.

出版信息

IEEE Open J Eng Med Biol. 2024 Jan 17;5:45-49. doi: 10.1109/OJEMB.2024.3355286. eCollection 2024.

DOI:10.1109/OJEMB.2024.3355286
PMID:38445241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10914145/
Abstract

Steerable needles are a novel technology that offers a wide range of uses in medical diagnostics and therapeutics. Currently, there exist several steerable needle designs in the literature, however, they are limited in their use by the number of possible turns, turn radius, and tissue damage. We introduce a novel design of a tape spring steerable needle, capable of multiple turns, that minimizes tissue damage. In this study, we measure the turning radius of our steerable needle in porcine liver tissue in vitro with ultrasound and estimate tissue damage in gel blocks using image analysis and 3D plaster casting. We were able to demonstrate our steerable needle's ability to steer through biological tissue, as well as introduce a novel method for estimating tissue damage. Our findings show that our needle design showed lower damage compared to similar designs in literature, as well as tissue stiffness being a protective factor against tissue damage.

摘要

可操纵针是一种新技术,在医学诊断和治疗中有广泛的用途。目前,文献中有几种可操纵针的设计,然而,它们在可能的转弯次数、转弯半径和组织损伤方面的应用受到限制。我们介绍了一种新型的带弹簧可操纵针设计,它能够进行多次转弯,并且能将组织损伤降至最低。在本研究中,我们在体外使用超声测量了可操纵针在猪肝组织中的转弯半径,并通过图像分析和三维石膏模型估计了凝胶块中的组织损伤。我们能够证明我们的可操纵针能够在生物组织中转向,并且引入了一种估计组织损伤的新方法。我们的研究结果表明,与文献中的类似设计相比,我们的针设计显示出更低的损伤,并且组织硬度是防止组织损伤的一个保护因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/af48c9cf3558/yim6-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/5a93ba270aab/yim1-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/0652d27ae29d/yim2-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/a6ba093a170e/yim3-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/2bf34d3acf87/yim4-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/4acdc76e160f/yim5-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/af48c9cf3558/yim6-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/5a93ba270aab/yim1-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/0652d27ae29d/yim2-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/a6ba093a170e/yim3-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/2bf34d3acf87/yim4-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/4acdc76e160f/yim5-3355286.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb0/10914145/af48c9cf3558/yim6-3355286.jpg

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本文引用的文献

1
Needle-like instruments for steering through solid organs: A review of the scientific and patent literature.用于在实体器官中引导的针状器械:科学文献与专利文献综述
Proc Inst Mech Eng H. 2017 Mar;231(3):250-265. doi: 10.1177/0954411916672149. Epub 2017 Jan 5.
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Methods for Improving the Curvature of Steerable Needles in Biological Tissue.改善生物组织中可控针曲率的方法。
IEEE Trans Biomed Eng. 2016 Jun;63(6):1167-77. doi: 10.1109/TBME.2015.2484262. Epub 2015 Oct 1.
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Effect of needle insertion speed on tissue injury, stress, and backflow distribution for convection-enhanced delivery in the rat brain.
针插入速度对大鼠脑内对流增强递送中组织损伤、应力和回流分布的影响。
PLoS One. 2014 Apr 28;9(4):e94919. doi: 10.1371/journal.pone.0094919. eCollection 2014.
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