Bragazzi Nicola Luigi, Woldegerima Woldegebriel Assefa, Siri Anna
Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON, Canada.
Department of Health Sciences (DISSAL), Postgraduate School of Public Health, University of Genoa, Genoa, Italy.
Front Microbiol. 2024 Feb 21;15:1305148. doi: 10.3389/fmicb.2024.1305148. eCollection 2024.
Microbial communities exhibit striking parallels with economic markets, resembling intricate ecosystems where microorganisms engage in resource exchange akin to human market transactions. This dynamic network of resource swapping mirrors economic trade in human markets, with microbes specializing in metabolic functions much like businesses specializing in goods and services. Cooperation and competition are central dynamics in microbial communities, with alliances forming for mutual benefit and species vying for dominance, similar to businesses seeking market share. The human microbiome, comprising trillions of microorganisms within and on our bodies, is not only a marker of socioeconomic status but also a critical factor contributing to persistent health inequalities. Social and economic factors shape the composition of the gut microbiota, impacting healthcare access and quality of life. Moreover, these microbes exert indirect influence over human decisions by affecting neurotransmitter production, influencing mood, behavior, and choices related to diet and emotions. Human activities significantly impact microbial communities, from dietary choices and antibiotic use to environmental changes, disrupting these ecosystems. Beyond their natural roles, humans harness microbial communities for various applications, manipulating their interactions and resource exchanges to achieve specific goals in fields like medicine, agriculture, and environmental science. In conclusion, the concept of microbial communities as biological markets offers valuable insights into their intricate functioning and adaptability. It underscores the profound interplay between microbial ecosystems and human health and behavior, with far-reaching implications for multiple disciplines. To paraphrase Alfred Marshall, "the Mecca of the economist lies in economic microbiology."
微生物群落与经济市场有着惊人的相似之处,类似于复杂的生态系统,其中微生物进行资源交换,类似于人类的市场交易。这种资源交换的动态网络反映了人类市场中的经济贸易,微生物专门从事代谢功能,就像企业专门生产商品和服务一样。合作与竞争是微生物群落的核心动态,为了互利而形成联盟,物种争夺主导地位,这与企业争夺市场份额类似。人类微生物组由我们体内和体表的数万亿微生物组成,不仅是社会经济地位的一个标志,也是导致持续健康不平等的一个关键因素。社会和经济因素塑造了肠道微生物群的组成,影响医疗保健的可及性和生活质量。此外,这些微生物通过影响神经递质的产生,对人类的决策产生间接影响,影响情绪、行为以及与饮食和情绪相关的选择。人类活动对微生物群落有重大影响,从饮食选择、抗生素使用到环境变化,都会破坏这些生态系统。除了它们的自然作用外,人类还将微生物群落用于各种应用,操纵它们的相互作用和资源交换,以在医学、农业和环境科学等领域实现特定目标。总之,将微生物群落视为生物市场的概念为其复杂的功能和适应性提供了有价值的见解。它强调了微生物生态系统与人类健康和行为之间的深刻相互作用,对多个学科都有深远影响。套用阿尔弗雷德·马歇尔的话来说,“经济学家的麦加在于经济微生物学”。