Department of Traditional Chinese Medicine, Feng Yuan Hospital, Ministry of Health and Welfare, Taipei, Taiwan, ROC.
Institute of Public Health, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2024 May 1;87(5):558-566. doi: 10.1097/JCMA.0000000000001083. Epub 2024 Mar 7.
According to the theory of traditional Chinese medicine (TCM), all types of body constitutions, except for the Gentleness (ie, the control group in our study), have disease susceptibility and affect the disease development process. This study attempted to investigate the relationship between TCM body constitutions and irritable bowel syndrome (IBS).
This cross-sectional study was based on Taiwan Biobank (TWB) and collected clinical data from 13 941 subjects aged 30 to 70. The results of the study showed that subjects with Yang-deficiency (N = 3161 subjects, odds ratio [OR] = 2.654, 95% CI = 1.740-3.910), Ying-deficiency (N = 3331 subjects, OR = 1.096, 95% CI = 0.627-1.782) or Stasis (N = 2335 subjects, OR = 1.680, 95% CI = 0.654-3.520) were more likely to have IBS.
If the subjects with two or more TCM body constitutions: Yang-deficiency + Ying-deficiency (OR = 3.948, 95% CI = 2.742-5.560), Yang-deficiency + Stasis (OR = 2.312, 95% CI = 1.170-4.112), Ying-deficiency + Stasis (OR = 1.851, 95% CI = 0.828-3.567), or Yang-deficiency + Ying-deficiency + Stasis (OR = 3.826, 95% CI = 2.954-4.932) were also prone to IBS.
These results confirmed the high correlation between TCM body constitutions and IBS. Because the current treatment for IBS is not entirely satisfactory, integrated traditional Chinese and Western medicine might provide patients with an alternative treatment option to alleviate IBS.
根据中医理论,除平和质(即本研究中的对照组)外,所有体质类型均具有疾病易感性,并影响疾病的发展过程。本研究试图探讨中医体质与肠易激综合征(IBS)的关系。
本横断面研究基于台湾生物银行(TWB),共纳入 13941 名 30-70 岁的研究对象。研究结果表明,阳虚质(N=3161 例,OR=2.654,95%CI=1.740-3.910)、阴虚质(N=3331 例,OR=1.096,95%CI=0.627-1.782)或血瘀质(N=2335 例,OR=1.680,95%CI=0.654-3.520)的患者更易患 IBS。
如果患者同时存在两种或两种以上中医体质:阳虚质+阴虚质(OR=3.948,95%CI=2.742-5.560)、阳虚质+血瘀质(OR=2.312,95%CI=1.170-4.112)、阴虚质+血瘀质(OR=1.851,95%CI=0.828-3.567)或阳虚质+阴虚质+血瘀质(OR=3.826,95%CI=2.954-4.932),也易患 IBS。
这些结果证实了中医体质与 IBS 之间存在高度相关性。由于目前 IBS 的治疗方法并不完全令人满意,因此中西医结合可能为患者提供一种缓解 IBS 的替代治疗选择。