Yu Tong, Zhang Zhennan, Xie Limin, Ke Xun, Liu Yang
Department of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Department of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Complement Ther Med. 2016 Dec;29:89-93. doi: 10.1016/j.ctim.2016.09.010. Epub 2016 Sep 12.
To explore the effects of traditional Chinese medicine (TCM) constitutions on repair capacity after osteonecrosis of the femoral head (ONFH).
Ninety-six patients with TCM constitutions of yang-deficiency, dampness-heat and/or blood-stasis were recruited from the orthopedic outpatient clinic of the Guang'anmen Hospital of the China Academy of Chinese Medical Science. Each patient underwent computed tomography (CT) examination of the hips, and CAD software was used to estimate proximal sclerosis ratios based on the CT images.
The proximal sclerosis ratios of subjects with different TCM constitutions were found to be significantly different (P=0.046): the ratios of subjects with the yang-deficiency, dampness-heat, blood-stasis, yang-deficiency plus dampness-heat, yang-deficiency plus blood-stasis, and dampness-heat plus blood-stasis constitutions were, respectively, 0.20±0.25, 0.24±0.25, 0.39±0.29, 0.29±0.37, 0.35±0.29, and 0.42±0.28. Differences among the three types of single, uneven constitutions were also observed (P=0.042).
For each pairwise comparison, the yang-deficiency constitution was different from the blood-stasis constitution (P=0.02) and dampness-heat plus blood-stasis constitution (p=0.02). The proximal sclerosis ratio was lower in the yang-deficiency constitution group but higher in the blood-stasis constitution group.
TCM constitutions influence the capacity for ONFH repair. The blood-stasis constitution has a strong repair ability, but the yang-deficiency constitution has a poor repair ability and tends to collapse and require positive treatment. Furthermore, important therapeutic principles should reinforce the kidney and strengthen the spleen.
探讨中医体质对股骨头坏死（ONFH）后修复能力的影响。
从中国中医科学院广安门医院骨科门诊招募96例阳虚、湿热和/或血瘀体质的患者。每位患者均接受了髋部计算机断层扫描（CT）检查，并使用CAD软件根据CT图像估算近端硬化率。
发现不同中医体质受试者的近端硬化率存在显著差异（P = 0.046）：阳虚、湿热、血瘀、阳虚兼湿热、阳虚兼血瘀、湿热兼血瘀体质受试者的硬化率分别为0.20±0.25、0.24±0.25、0.39±0.29、0.29±0.37、0.35±0.29和0.42±0.28。还观察到三种单一、不均衡体质类型之间存在差异（P = 0.042）。
在每对比较中，阳虚体质与血瘀体质（P = 0.02）和湿热兼血瘀体质（P = 0.02）不同。阳虚体质组的近端硬化率较低，而血瘀体质组的较高。
中医体质影响ONFH的修复能力。血瘀体质具有较强的修复能力，而阳虚体质的修复能力较差，易于塌陷，需要积极治疗。此外，重要的治疗原则应是补肾健脾。
