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人工养殖巴塔戈尼亚野兔(Dolichotis patagonum)的抗凝血灭鼠剂中毒。

Anticoagulant rodenticide poisoning in farmed Patagonian mara (Dolichotis patagonum).

机构信息

Department of Veterinary Pharmacology, Faculty of Veterinary Science, Chulalongkorn University, Henri - Dunant Road, Pathumwan, Bangkok, 10330, Thailand.

Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Henri - Dunant Road, Pathumwan, Bangkok, 10330, Thailand.

出版信息

BMC Vet Res. 2024 Mar 7;20(1):83. doi: 10.1186/s12917-024-03943-x.

DOI:10.1186/s12917-024-03943-x
PMID:38454460
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10921809/
Abstract

BACKGROUND

Anticoagulant rodenticide (AR) poisoning was diagnosed in 3 Patagonian maras (Dolichotis patagonum) raised in the mara farm in Thailand. To date, there have been no reports of maras with diagnosed AR poisoning.

CASE PRESENTATION

The first clinical sign of the sickening maras was anorexia. Fifteen from 50 maras were dead over a 3-5 day period after the clinical signs had occurred. Positive results to AR were detected in all of the maras' liver specimens by screening test using thin layer chromatography and spectrophotometry methods. Supportive therapy was selected for the treatment of the 35 surviving maras. During the follow - up observation period of 12 months, all of the surviving maras were healthy and no reproductive loss.

CONCLUSIONS

This is the first report on suspected AR poisoning in maras in Thailand based on history taking, clinical signs, gross pathology lesions and chemical analysis. AR poisoning in the present report is possibly from contaminated animal food. Therefore, quality control of food should be fastidious when feeding maras.

摘要

背景

在泰国的 mara 农场饲养的 3 只巴塔戈尼亚马鹿(Dolichotis patagonum)被诊断出患有抗凝血灭鼠剂(AR)中毒。迄今为止,尚无马鹿 AR 中毒的报告。

病例介绍

患病马鹿的第一个临床症状是食欲不振。在出现临床症状后的 3-5 天内,50 只马鹿中有 15 只死亡。用薄层色谱法和分光光度法进行筛选试验,在所有马鹿的肝脏标本中均检测到 AR 呈阳性。对 35 只幸存的马鹿进行了支持性治疗。在 12 个月的随访观察期内,所有幸存的马鹿均健康,无繁殖损失。

结论

这是根据病史、临床症状、大体病理损伤和化学分析,首次在泰国报告的马鹿疑似 AR 中毒病例。本报告中的 AR 中毒可能来自受污染的动物饲料。因此,饲养马鹿时应严格控制食物质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d848/10921809/34dc13eca911/12917_2024_3943_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d848/10921809/9f3a0a02a89f/12917_2024_3943_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d848/10921809/34dc13eca911/12917_2024_3943_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d848/10921809/9f3a0a02a89f/12917_2024_3943_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d848/10921809/34dc13eca911/12917_2024_3943_Figb_HTML.jpg

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