Pharmacy Practice and Science Department University of Kentucky Lexington KY.
Department of Neurology University of Kentucky Lexington KY.
J Am Heart Assoc. 2024 Mar 19;13(6):e032916. doi: 10.1161/JAHA.123.032916. Epub 2024 Mar 8.
Contemporary data describing the national trends on vascular risk factor control among stroke survivors are limited.
This is a cross-sectional analysis of the National Health and Nutrition Examination Survey cycles 2009 to 2010 to 2017 to March 2020. Adults (≥18 years of age) with a self-reported diagnosis of stroke were identified. Age-adjusted trends in hypertension, diabetes, and hyperlipidemia control were examined. Sex and racial differences in vascular risk factor control were also investigated. Among 32 497 adult individuals who participated in the National Health and Nutrition Examination Survey, 1354 participants (4.2%) self-reported a prior diagnosis of stroke (55% were women). The rates of age-adjusted blood pressure control worsened when using the cutoff <140/90 mm Hg (79.1% in 2009-2010 versus 61.5% in 2017-March 2020, <0.001) and using the cutoff <130/80 mm Hg (53.3% in 2009-2010 versus 38.6% in 2017-March 2020, =0.006). Age-adjusted diabetes control (hemoglobin A1c <7 mg/dL) did not significantly change during the study period (88.8% in 2009-2010 versus 85.9% in 2017-March 2020, =0.41). Achieving a total cholesterol level <200 mg/dL did not change during the study period (67.3% in 2009-2010 versus 73.3% in 2017-March 2020, =0.16). These findings were mostly consistent in men and women and across the different racial and ethnic groups.
In the United States, secondary prevention was suboptimal for stroke survivors, and there has not been any major significant improvement in the rates of achieving the recommended targets for vascular risk factors during the past decade. These findings highlight the need for targeted interventions to improve these modifiable risk factors.
目前有关美国脑卒中幸存者血管风险因素控制的全国性趋势数据有限。
这是一项基于美国国家健康和营养调查(National Health and Nutrition Examination Survey,NHANES)2009 年至 2010 年至 2017 年 3 月至 2020 年 3 月的周期的横断面分析。入选标准为自我报告患有脑卒中的成年人(≥18 岁)。本研究分析了高血压、糖尿病和血脂异常控制的年龄调整趋势,并探讨了血管风险因素控制方面的性别和种族差异。在参加 NHANES 的 32497 名成年人中,有 1354 名(4.2%)参与者自我报告曾患有脑卒中(55%为女性)。当使用<140/90mmHg(2009-2010 年为 79.1%,2017-2020 年 3 月为 61.5%,<0.001)和<130/80mmHg(2009-2010 年为 53.3%,2017-2020 年 3 月为 38.6%,=0.006)的切点时,年龄调整后的血压控制率恶化。在研究期间,糖化血红蛋白(hemoglobin A1c)<7mg/dL 的糖尿病控制(年龄调整)没有显著变化(2009-2010 年为 88.8%,2017-2020 年 3 月为 85.9%,=0.41)。在研究期间,总胆固醇水平<200mg/dL 的患者比例没有变化(2009-2010 年为 67.3%,2017-2020 年 3 月为 73.3%,=0.16)。这些发现无论是在男性和女性中,还是在不同种族和民族群体中都基本一致。
在美国,脑卒中幸存者的二级预防效果不佳,在过去十年中,实现血管风险因素推荐目标的比率没有任何显著改善。这些发现突显了有必要采取有针对性的干预措施来改善这些可改变的风险因素。