Universidad Adolfo Ibáñez, Peñalolén, Santiago de Chile, Chile.
Business School, Universidad Adolfo Ibáñez, Peñalolén, Santiago de Chile, Chile.
Nicotine Tob Res. 2024 Aug 22;26(9):1166-1174. doi: 10.1093/ntr/ntae045.
The harmful effects of first and secondhand smoking are well-established. Smoke-free laws aim at protecting nonsmokers. This study aimed to assess the impact of the 2013 total ban on indoor smoking in Chile on hospitalizations and deaths of major cardiovascular events.
The logarithm of the monthly hospitalization and death rates, standardized by age for every 100 000 inhabitants, were estimated for ischemic heart disease, acute myocardial infarction, strokes, and a composite outcome of ischemic heart diseases (which includes acute myocardial infarction) and strokes. In addition, interrupted time series with synthetic control groups were used to assess changes in levels and trends after the intervention.
The total ban on indoor smoking caused significant reductions in death rates for the three diseases studied for age groups above 20 years old. In addition, there were substantial decreases in the post-intervention hospitalization rates for ischemic heart disease: for the 20-44 age group, the decrease was 8.7% compared to the pre-intervention period (p < .01). In comparison, such a reduction was 4% (p < .01) for the ≥65 age group. For acute myocardial infarction, the decrease was 11.5% (p < .01) for the 20-44 age group, while for stroke, it was a 1.2% (p < .01) decrease for the total population. It is estimated that the smoking ban averted 15.6% of the deaths compared with the synthetic control groups.
The implementation of total smoke-free environments in Chile contributed to the reduction of mortality for main cardiovascular diseases. This study provides additional evidence of causality linking the policy to health outcomes.
The total indoor smoking ban significantly affected age-standardized hospitalization and deaths. The number of deaths averted by this policy is estimated at approximately 4758 and 5256 for IHD and stroke, respectively, during the 2013-2017 period (15.6% fewer deaths than predicted by the synthetic control groups). The study contributes to the body of evidence that supports total indoor smoking bans.
第一手和第二手吸烟的有害影响已得到充分证实。无烟法律旨在保护不吸烟者。本研究旨在评估 2013 年智利全面禁止室内吸烟对主要心血管事件住院和死亡的影响。
对缺血性心脏病、急性心肌梗死、中风以及缺血性心脏病(包括急性心肌梗死)和中风的复合结局每 10 万居民的年龄标准化每月住院率和死亡率的对数进行估计。此外,还使用中断时间序列和合成对照组来评估干预后的水平和趋势变化。
全面禁止室内吸烟导致 20 岁以上人群三种疾病的死亡率显著下降。此外,缺血性心脏病的住院率在干预后大幅下降:对于 20-44 岁年龄组,与干预前相比下降了 8.7%(p<0.01)。相比之下,≥65 岁年龄组的降幅为 4%(p<0.01)。对于急性心肌梗死,20-44 岁年龄组的降幅为 11.5%(p<0.01),而对于中风,总人群的降幅为 1.2%(p<0.01)。据估计,与合成对照组相比,禁烟措施避免了 15.6%的死亡。
智利全面实施无烟环境有助于降低主要心血管疾病的死亡率。本研究提供了将政策与健康结果联系起来的因果关系的额外证据。
全面室内禁烟显著影响年龄标准化的住院和死亡。这项政策避免的死亡人数估计在 15.6%左右,即 2013-2017 年期间,与合成对照组相比,IHD 和中风分别减少了 4758 人和 5256 人(比预测的少 15.6%)。该研究为支持全面室内禁烟的证据体系做出了贡献。