类器官的前景与挑战：从人源化到人类来源。
Promises and challenges of organoids: From humanized to human derived.
机构信息
Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing 100084, China.
出版信息
Cell Stem Cell. 2024 Mar 7;31(3):281-282. doi: 10.1016/j.stem.2024.02.002.
PMID:38458173
Abstract
Kastenschmidt et al. present a groundbreaking organoid culture model for follicular lymphoma, which is capable of maintaining stable compositions of B and T cells. This model is utilized in testing bispecific antibodies in effective killing of tumor B cells with the activation of T cells.
摘要
卡斯滕施密特等人提出了一种滤泡性淋巴瘤的开创性类器官培养模型，该模型能够维持 B 细胞和 T 细胞的稳定组成。该模型用于测试双特异性抗体，以有效杀死肿瘤 B 细胞并激活 T 细胞。
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