Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing 100084, China.
Cell Stem Cell. 2024 Mar 7;31(3):281-282. doi: 10.1016/j.stem.2024.02.002.
Kastenschmidt et al. present a groundbreaking organoid culture model for follicular lymphoma, which is capable of maintaining stable compositions of B and T cells. This model is utilized in testing bispecific antibodies in effective killing of tumor B cells with the activation of T cells.
卡斯滕施密特等人提出了一种滤泡性淋巴瘤的开创性类器官培养模型，该模型能够维持 B 细胞和 T 细胞的稳定组成。该模型用于测试双特异性抗体，以有效杀死肿瘤 B 细胞并激活 T 细胞。
