Dawodu A H, Alausa O K
Afr J Med Med Sci. 1980 Mar-Jun;9(1-2):1-6.
This review has shown a high incidence of neonatal septicaemia in a tropical environment. The predisposing factors leading to increased incidence of primary septicaemia include low maternal socioeconomic status, lack of adequate prenatal care, unsterile delivery practices in those born at home and increased incidence of susceptible hosts. Apart from gram-negative organisms, Staphylococcus aureus was the next common agent responsible for neonatal septicaemia. A combination of penicillinase-resistant penicillin and an eminoglycoside in particular gentamycin, should be the initial antibiotic of choice in suspected cases of neonatal septicaemia. Suggestions for reduction in the incidence of neonatal septicaemia were discussed.
本综述显示,在热带环境中新生儿败血症的发病率很高。导致原发性败血症发病率增加的诱发因素包括母亲社会经济地位低下、缺乏足够的产前护理、在家出生者的分娩操作不无菌以及易感宿主的发病率增加。除革兰氏阴性菌外,金黄色葡萄球菌是导致新生儿败血症的下一个常见病原体。对于疑似新生儿败血症病例,初始抗生素选择应为耐青霉素酶青霉素与氨基糖苷类药物(尤其是庆大霉素)联合使用。文中还讨论了降低新生儿败血症发病率的建议。