Shehata Mostafa, Al Hosani Ibrahim, Ahmed Ishtiaq, Abu Alkas Heba, Khaddam Omar, Aljanahi Abd Allah, Al Ahmad Maryam, Al Tiniji Khalifa, Singh Yashbir, Malik Talha
Gastroenterology, Sheikh Shakhbout Medical City (SSMC), Abu Dhabi, ARE.
Internal Medicine, Sheikh Shakhbout Medical City (SSMC), Abu Dhabi, ARE.
Cureus. 2024 Mar 7;16(3):e55741. doi: 10.7759/cureus.55741. eCollection 2024 Mar.
Percutaneous endoscopic gastrostomy (PEG) tube placement is generally safe but is associated with a range of complications. Minor complications include infections, granuloma formation, leakage, and blockages, while major complications encompass aspiration pneumonia, hemorrhage, and more serious conditions such as necrotizing fasciitis and colonic fistula.
This study aimed to assess the rate of short-term complications within one month of endoscopic PEG insertion, focusing on their correlation with patient characteristics.
This retrospective cohort study analyzed data from patients who underwent PEG insertion between January 2020 and December 2022. It evaluated the incidence of complications in relation to variables such as the indication for the procedure, the patient's immune status, albumin and CRP levels, and the setting of the procedure (inpatient vs. outpatient).
The study included 121 patients, with a mean age of 69.73 years, comprising 71 males (58.7%) and 50 females (41.3%). Neurological indications accounted for 64.5% of the cases. Notably, 67.8% of the patients were immunocompromised. Within 30 days of PEG insertion, 16.5% experienced complications, including GI bleeding (4.1%), infection at the PEG site (11.6%), and peritonitis (0.8%). Complications were significantly higher in immunocompromised patients and those with non-neurological indications. Higher serum albumin and lower CRP levels were associated with fewer complications, though the association was not statistically significant.
The study highlights that gastrostomy site infection is the most common short-term complication following PEG insertion. Immune status and the reason for PEG insertion emerged as key factors influencing the likelihood of complications.
经皮内镜下胃造口术（PEG）置管通常是安全的，但会伴有一系列并发症。轻微并发症包括感染、肉芽肿形成、渗漏和堵塞，而严重并发症则包括吸入性肺炎、出血以及更严重的情况，如坏死性筋膜炎和结肠瘘。
本研究旨在评估内镜下PEG置管后1个月内的短期并发症发生率，重点关注其与患者特征的相关性。
这项回顾性队列研究分析了2020年1月至2022年12月期间接受PEG置管的患者数据。评估了与手术指征、患者免疫状态、白蛋白和CRP水平以及手术环境（住院患者与门诊患者）等变量相关的并发症发生率。
该研究纳入了121名患者，平均年龄为69.73岁，其中男性71名（58.7%），女性50名（41.3%）。神经学指征占病例的64.5%。值得注意的是，67.8%的患者免疫功能低下。在PEG置管后30天内，16.5%的患者出现并发症，包括胃肠道出血（4.1%）、PEG部位感染（11.6%）和腹膜炎（0.8%）。免疫功能低下的患者和有非神经学指征的患者并发症明显更高。血清白蛋白水平较高和CRP水平较低与较少的并发症相关，尽管这种关联在统计学上不显著。
该研究强调胃造口部位感染是PEG置管后最常见的短期并发症。免疫状态和PEG置管的原因是影响并发症发生可能性的关键因素。
