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胆汁回输纠正高流量外引流胆汁所致严重低钠血症：一例报告

Severe hyponatraemia due to high output external biliary drainage corrected with bile refeeding: A case report.

作者信息

Subasinghe Duminda, Dassanayake Preethi, Jayasinghe Ravindri, Pathmanathan Sivatharshya, Dassanyake Vihara, Sivaganesh Sivasuriya

机构信息

University Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.

Division of HPB Surgery,Department of Surgery, Faculty of Medicine, University of Colombo , Sri Lanka.

出版信息

SAGE Open Med Case Rep. 2024 Mar 8;12:2050313X241237612. doi: 10.1177/2050313X241237612. eCollection 2024.

DOI:10.1177/2050313X241237612
PMID:38463452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10924539/
Abstract

Hyponatraemia is an uncommon complication of external biliary drainage. We report on a 62-year-old male with hilar cholangiocarcinoma who developed refractory severe hyponatraemia despite sodium replacement during preoperative external biliary drainage. Nasojejunal bile refeeding restored sodium levels to normal.

摘要

低钠血症是体外胆汁引流的一种罕见并发症。我们报告一例62岁男性肝门部胆管癌患者，该患者在术前体外胆汁引流期间尽管补充了钠，但仍发生了难治性严重低钠血症。经鼻空肠胆汁回输使钠水平恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/3407cf1834c6/10.1177_2050313X241237612-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/9aed4261c41b/10.1177_2050313X241237612-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/7461c83febe8/10.1177_2050313X241237612-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/a2ead3454eea/10.1177_2050313X241237612-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/ec25bc32966f/10.1177_2050313X241237612-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/3407cf1834c6/10.1177_2050313X241237612-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/9aed4261c41b/10.1177_2050313X241237612-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/7461c83febe8/10.1177_2050313X241237612-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/a2ead3454eea/10.1177_2050313X241237612-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/ec25bc32966f/10.1177_2050313X241237612-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce1/10924539/3407cf1834c6/10.1177_2050313X241237612-fig5.jpg

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本文引用的文献

1
Oral Bile Reinfusion in Chronic Percutaneous Transhepatic Cholangiodrainage.慢性经皮经肝胆道引流术中的口服胆汁回输
ACG Case Rep J. 2020 Jul 10;7(7):e00421. doi: 10.14309/crj.0000000000000421. eCollection 2020 Jul.
2
Hyponatremia is a Predictor of Clinical Outcome for Resected Biliary Tract Cancers: A Retrospective Single-Center Study.低钠血症是切除的胆管癌临床预后的一个预测指标：一项回顾性单中心研究。
Oncol Ther. 2020 Jun;8(1):115-124. doi: 10.1007/s40487-020-00112-6. Epub 2020 Apr 1.
3
Severe Persistent Hyponatremia: A Rare Presentation of Biliary Fluid Loss.
严重持续性低钠血症：胆汁液丢失的一种罕见表现。
J Investig Med High Impact Case Rep. 2019 Jan-Dec;7:2324709619869379. doi: 10.1177/2324709619869379.
4
Clinical practice guideline on diagnosis and treatment of hyponatraemia.临床实践指南：低钠血症的诊断与治疗。
Intensive Care Med. 2014 Mar;40(3):320-31. doi: 10.1007/s00134-014-3210-2. Epub 2014 Feb 22.
5
Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations.低钠血症的诊断、评估和治疗：专家小组建议。
Am J Med. 2013 Oct;126(10 Suppl 1):S1-42. doi: 10.1016/j.amjmed.2013.07.006.
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Bile formation and secretion.胆汁的形成和分泌。
Compr Physiol. 2013 Jul;3(3):1035-78. doi: 10.1002/cphy.c120027.
7
Effectiveness and safety of preoperative percutaneous transhepatic cholangiodrainage with bile re-infusion in patients with hilar cholangiocarcinoma: a retrospective controlled study.术前经皮经肝胆管引流胆汁再注入治疗肝门部胆管癌的疗效和安全性：一项回顾性对照研究。
Am J Med Sci. 2013 Nov;346(5):353-7. doi: 10.1097/MAJ.0b013e3182755de6.
8
[Effect of percutaneous transhepatic cholangial drainage with bile reinfusion and enteral nutrition via the nasojejunal tube on visceral protein and hepatic function].经皮经肝胆道引流联合胆汁回输及经鼻空肠管肠内营养对内脏蛋白及肝功能的影响
Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jan;30(1):146-8.
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Tumor-related hyponatremia.肿瘤相关性低钠血症
Clin Med Res. 2007 Dec;5(4):228-37. doi: 10.3121/cmr.2007.762. Epub 2007 Dec 17.
10
High-volume postobstructive choleresis after transhepatic external biliary drainage resolves with conversion to internal drainage.
J Clin Gastroenterol. 1993 Jul;17(1):42-5. doi: 10.1097/00004836-199307000-00012.