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一名女童患甲型肝炎感染并发完全性心脏传导阻滞，最终死亡。

Complete heart block associated with hepatitis A infection in a female child with fatal outcome.

作者信息

Ahmed Mansoor, Naseer Haseena, Ebad Ur Rehman Mohammad, Basit Jawad, Nashwan Abdulqadir J, Arshad Mateen, Ahmad Afnan, Asad Muhammad

机构信息

Department of Cardiology, Holy Family Hospital, Rawalpindi Medical University, Rawalpindi, Pakistan.

Department of Pediatrics, Fauji Foundation Hospital, Foundation University Medical College, Islamabad, Pakistan.

出版信息

Open Med (Wars). 2024 Feb 5;19(1):20240905. doi: 10.1515/med-2024-0905. eCollection 2024.

DOI:10.1515/med-2024-0905
PMID:38463516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10921436/
Abstract

Hepatitis A virus (HAV) infection can cause extra-hepatic manifestations like myocarditis. An 8-year-old female with HAV infection presented with fever, abdominal pain, vomiting, and icterus. She developed viral myocarditis with complete AV dissociation on ECG and was treated with a temporary pacemaker, but her condition worsened, and she died. Hepatitis A viral infection can be associated with viral myocarditis and complete heart block that can lead to cardiogenic shock and death eventually.

摘要

甲型肝炎病毒（HAV）感染可引起如心肌炎等肝外表现。一名8岁感染HAV的女性出现发热、腹痛、呕吐和黄疸。她发展为病毒性心肌炎，心电图显示完全性房室分离，并接受了临时起搏器治疗，但病情恶化，最终死亡。甲型肝炎病毒感染可能与病毒性心肌炎和完全性心脏传导阻滞相关，最终可导致心源性休克和死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/58a00c42ed77/j_med-2024-0905-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/de36a030e3d3/j_med-2024-0905-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/3f73f1073c53/j_med-2024-0905-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/58a00c42ed77/j_med-2024-0905-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/de36a030e3d3/j_med-2024-0905-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/3f73f1073c53/j_med-2024-0905-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/10921436/58a00c42ed77/j_med-2024-0905-fig003.jpg

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本文引用的文献

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Diagnosis and Management of Myocarditis in Children: A Scientific Statement From the American Heart Association.儿童心肌炎的诊断和治疗：美国心脏协会的科学声明。
Circulation. 2021 Aug 10;144(6):e123-e135. doi: 10.1161/CIR.0000000000001001. Epub 2021 Jul 7.
2
Hepatitis A vaccination and its immunological and epidemiological long-term effects - a review of the evidence.甲型肝炎疫苗接种及其免疫和流行病学的长期效果——证据综述。
Hum Vaccin Immunother. 2021 May 4;17(5):1496-1519. doi: 10.1080/21645515.2020.1819742. Epub 2020 Dec 16.
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Case report of an isolated myocarditis due to COVID-19 infection in a paediatric patient.
一名儿科患者因新型冠状病毒肺炎（COVID-19）感染导致孤立性心肌炎的病例报告。
Eur Heart J Case Rep. 2020 Jul 3;4(FI1):1-5. doi: 10.1093/ehjcr/ytaa180. eCollection 2020 Oct.
4
Case report: high-grade atrioventricular block in suspected COVID-19 myocarditis.病例报告：疑似新型冠状病毒肺炎心肌炎伴高度房室传导阻滞
Eur Heart J Case Rep. 2020 Aug 25;4(FI1):1-6. doi: 10.1093/ehjcr/ytaa248. eCollection 2020 Oct.
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A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis-A Case Report with Literature Review.甲型肝炎感染的一种非常罕见的并发症：急性心肌炎——一例报告并文献复习
Case Rep Med. 2018 Sep 13;2018:3625139. doi: 10.1155/2018/3625139. eCollection 2018.
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A case report of myocarditis combined with hepatitis caused by herpes simplex virus.单纯疱疹病毒引起的心肌炎合并肝炎病例报告
BMC Cardiovasc Disord. 2018 Jul 3;18(1):134. doi: 10.1186/s12872-018-0869-2.
7
Outcomes of Heart Block in Myocarditis: A Review of 31,760 Patients.心肌炎中心脏传导阻滞的结局：对31760例患者的综述
Heart Lung Circ. 2019 Feb;28(2):272-276. doi: 10.1016/j.hlc.2017.12.005. Epub 2017 Dec 24.
8
Hepatitis A, cardiomyopathy, aplastic anemia, and acute liver failure: A devastating scenario.甲型肝炎、心肌病、再生障碍性贫血和急性肝衰竭：一种灾难性的情况。
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