Wu Jian-Jun, Xian Hui-Min, Yang Da-Wei, Yang Fan
Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
Department of Orthopedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
World J Orthop. 2024 Feb 18;15(2):101-104. doi: 10.5312/wjo.v15.i2.101.
Over the course of several decades, robust research has firmly established the significance of mitochondrial pathology as a central contributor to the onset of skeletal muscle atrophy in individuals with diabetes. However, the specific intricacies governing this process remain elusive. Extensive evidence highlights that individuals with diabetes regularly confront the severe consequences of skeletal muscle degradation. Deciphering the sophisticated mechanisms at the core of this pathology requires a thorough and meticulous exploration into the nuanced factors intricately associated with mitochondrial dysfunction.
在几十年的时间里,强有力的研究已确凿地证实了线粒体病理学作为糖尿病患者骨骼肌萎缩发病的核心因素的重要性。然而,控制这一过程的具体复杂细节仍不清楚。大量证据表明,糖尿病患者经常面临骨骼肌退化的严重后果。要破解这种病理学核心的复杂机制,需要对与线粒体功能障碍错综复杂相关的细微因素进行全面而细致的探究。