Suppr超能文献

2型糖尿病中的线粒体功能障碍:骨骼肌萎缩的一条被忽视的途径。

Mitochondrial dysfunction in type 2 diabetes: A neglected path to skeletal muscle atrophy.

作者信息

Wu Jian-Jun, Xian Hui-Min, Yang Da-Wei, Yang Fan

机构信息

Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.

Department of Orthopedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.

出版信息

World J Orthop. 2024 Feb 18;15(2):101-104. doi: 10.5312/wjo.v15.i2.101.

Abstract

Over the course of several decades, robust research has firmly established the significance of mitochondrial pathology as a central contributor to the onset of skeletal muscle atrophy in individuals with diabetes. However, the specific intricacies governing this process remain elusive. Extensive evidence highlights that individuals with diabetes regularly confront the severe consequences of skeletal muscle degradation. Deciphering the sophisticated mechanisms at the core of this pathology requires a thorough and meticulous exploration into the nuanced factors intricately associated with mitochondrial dysfunction.

摘要

在几十年的时间里,强有力的研究已确凿地证实了线粒体病理学作为糖尿病患者骨骼肌萎缩发病的核心因素的重要性。然而,控制这一过程的具体复杂细节仍不清楚。大量证据表明,糖尿病患者经常面临骨骼肌退化的严重后果。要破解这种病理学核心的复杂机制,需要对与线粒体功能障碍错综复杂相关的细微因素进行全面而细致的探究。

相似文献

9
Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle.运动对肥胖诱导的骨骼肌线粒体功能障碍的影响。
Korean J Physiol Pharmacol. 2017 Nov;21(6):567-577. doi: 10.4196/kjpp.2017.21.6.567. Epub 2017 Oct 30.

本文引用的文献

6
Mitochondrial dynamics and mitochondrial quality control.线粒体动力学与线粒体质量控制
Redox Biol. 2015;4:6-13. doi: 10.1016/j.redox.2014.11.006. Epub 2014 Nov 20.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验