Pereira Austin, Nichani Prem A H, Yan Peng, Micieli Jonathan A
Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, ON, Canada.
Kensington Vision and Research Centre, Toronto, ON, Canada.
J Vitreoretin Dis. 2024 Jan 2;8(2):192-195. doi: 10.1177/24741264231218539. eCollection 2024 Mar-Apr.
To present a rare case of subfoveal choroidal neovascular membrane (CNVM) secondary to idiopathic intracranial hypertension. A case was evaluated. A 21-year-old woman presented with a 2-week history of painless blurred vision in the right eye. She described initial metamorphopsia and intermittent bitemporal headaches lasting 30 minutes. She denied pain with eye movements and a history of trauma. Her body mass index was 49 kg/m. The visual acuity (VA) was 20/320 OD and 20/20 OS; there was no relative afferent pupillary defect. A dilated fundus examination showed bilateral optic disc edema and a subfoveal CNVM in the right eye. The patient was started on oral acetazolamide 500 mg twice daily and treated with 2 intravitreal antivascular endothelial growth factor (anti-VEGF) injections. Three months later, the VA was 20/30 in the right eye and the disc edema had improved. CNVMs in the setting of idiopathic intracranial hypertension-related papilledema may be subfoveal and have an excellent response to anti-VEGF agents.
报告一例继发于特发性颅内高压的黄斑下脉络膜新生血管膜(CNVM)罕见病例。对一例患者进行了评估。一名21岁女性,右眼出现无痛性视力模糊2周。她最初描述有视物变形和间歇性双侧颞部头痛,持续30分钟。她否认眼球运动时疼痛及外伤史。她的体重指数为49kg/m。右眼视力(VA)为20/320,左眼视力为20/20;无相对性传入瞳孔障碍。散瞳眼底检查显示双侧视盘水肿,右眼有黄斑下CNVM。患者开始口服乙酰唑胺,每日两次,每次500mg,并接受2次玻璃体内抗血管内皮生长因子(抗VEGF)注射治疗。3个月后,右眼视力为20/30,视盘水肿有所改善。特发性颅内高压相关视乳头水肿情况下的CNVM可能位于黄斑下,对抗VEGF药物有良好反应。