Morse P H, Leveille A S, Antel J P, Burch J V
Am J Ophthalmol. 1981 Mar;91(3):312-7. doi: 10.1016/0002-9394(81)90282-8.
A 32-year-old obese woman with hypertension and a three-year history of pseudotumor cerebri developed bilateral juxtapapillary subretinal neovascular membranes. To our knowledge, this is the first reported case of bilateral subretinal neovascular membranes complicating the course of this disease. The subretinal neovascular membrane in the left eye spontaneously involuted, but because the membrane in the right eye threatened the foveola, the patient underwent argon-laser photocoagulation. The subretinal fluid and hemorrhage progressively resolved, the membrane was replaced by fibrous tissue, and visual acuity improved. The pathogenesis of the subretinal neovascular membranes was presumably secondary to pressure deformity of the border of Bruch's membrane at the optic disk, creating a discontinuity of normal anatomic apposition of the chorioretinal layers. This anatomic dehiscence, coupled with hypoxia created by axonal tissue swelling and resultant impaired vascular perfusion of the tissues, led to the development of subretinal neovascular membranes.
一名32岁的肥胖女性，患有高血压，并有三年的假性脑瘤病史，出现了双侧紧邻视乳头的视网膜下新生血管膜。据我们所知，这是首例报道的双侧视网膜下新生血管膜使该病病程复杂化的病例。左眼的视网膜下新生血管膜自发消退，但由于右眼的新生血管膜威胁到黄斑中心小凹，患者接受了氩激光光凝治疗。视网膜下液和出血逐渐消退，新生血管膜被纤维组织取代，视力得到改善。视网膜下新生血管膜的发病机制可能继发于视盘处布鲁赫膜边界的压力变形，导致脉络膜视网膜层正常解剖对合的连续性中断。这种解剖学裂开，再加上轴突组织肿胀导致的缺氧以及由此引起的组织血管灌注受损，导致了视网膜下新生血管膜的形成。
