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地域差异和溶剂变化对提取物的酚类成分、抗氧化活性和抗菌功效的影响。

Effect of regional disparities and solvent variations on the phenolic composition, antioxidant activity, and antibacterial efficacy of extracts.

机构信息

Laboratory of Bioactive Substances, Centre of Biotechnology of Borj-Cedria, Hammam-Lif, Tunisia.

Laboratory of Aromatic and Medicinal Plants, Centre of Biotechnology of Borj-Cedria, Hammam-Lif, Tunisia.

出版信息

Int J Environ Health Res. 2024 Nov;34(11):3810-3819. doi: 10.1080/09603123.2024.2327521. Epub 2024 Mar 11.

DOI:10.1080/09603123.2024.2327521
PMID:38465659
Abstract

The ethyl acetate, ethanol, methanol, and water extracts of cypress from three Tunisian regions (Bizerte, Ben Arous, and Nabeul) were reported for their phenolic content, antioxidant, and antibacterial activities. Cypress extract had an important antiradical and antibacterial potential which was strongly related to the organoleptic quality of the extract which appeared strongly region dependent. The highest contents of polyphenols were obtained in the methanol extract at the region of Bizerte (315.75 mg GAE/g DW). Cupressuflavone was the major compound with high proportions in methanol extract of Bizerte (68%). Amentoflavone also constituted an important flavonoid compound presented in higher proportion in the ethyl acetate extract of Ben Arous (21.2%). For Gram-positive bacteria strains, was sensitive to the ethanol extract of Nabeul with IZ = 40 mm. This study suggests cypress as potential natural source of antioxidants and antibacterial agents.

摘要

来自突尼斯三个地区(比塞大、本阿鲁斯和纳布勒)的柏木的乙酸乙酯、乙醇、甲醇和水提取物,其酚类含量、抗氧化和抗菌活性均有报道。柏木提取物具有重要的抗自由基和抗菌潜力,这与提取物的感官质量密切相关,而感官质量又强烈依赖于地区。在比塞大地区的甲醇提取物中,多酚含量最高(315.75mg GAE/g DW)。柏黄酮是甲醇提取物中含量较高的主要化合物(68%)。金松双黄酮也是一种重要的类黄酮化合物,在本阿鲁斯的乙酸乙酯提取物中以较高的比例存在(21.2%)。对于革兰氏阳性菌菌株,纳布勒的乙醇提取物对其敏感,IZ=40mm。本研究表明柏木是抗氧化剂和抗菌剂的潜在天然来源。

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