Trabelsi Becem, Ghorbel Sahar, Ben Rabeh Rania, Bouassida Mahdi, Ben Ali Mechaal
Department of Anesthesiology and Intensive Care, Taher Maamouri Teaching Hospital of Nabeul, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Pediatric Department C, Bechir Hamza Children's Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Tunis Med. 2023 Oct 5;101(10):756-758.
The early diagnosis of pneumonia following severe blunt chest trauma (SBCT) allows the early prescription of antibiotics and initiation of adequate supportive care.
To assess the usefulness of C-reactive protein (CRP) in the early diagnosis of pneumonia complicating SBCT.
We conducted a prospective study of patients admitted to trauma intensive care unit for SBCT between January 2020 and February 2023. Patients were divided into two groups according to whether or not they developed pneumonia. The CRP levels were monitored daily.
One hundred sixty-seven patients were included. Pneumonia occurred in 40.1% of patients within a median of 5 days. We found statistically significant difference in mean CRP levels between groups from day 3 to day 9 following trauma. The increase in CRP level on the 4th day from a value greater than or equal to 192 mg/L was a marker of early diagnosis of pneumonia (sensitivity 80.6%; specificity 80.8%).
Daily CRP measurement from the 3rd day following SBCT may be useful for early diagnosis of pneumonia complicating SBCT.
严重钝性胸部创伤（SBCT）后肺炎的早期诊断有助于早期使用抗生素并开始进行充分的支持治疗。
评估C反应蛋白（CRP）在SBCT并发肺炎早期诊断中的作用。
我们对2020年1月至2023年2月因SBCT入住创伤重症监护病房的患者进行了一项前瞻性研究。根据患者是否发生肺炎将其分为两组。每天监测CRP水平。
共纳入167例患者。40.1%的患者在中位时间5天内发生肺炎。我们发现创伤后第3天至第9天两组之间的平均CRP水平存在统计学显著差异。第4天CRP水平从大于或等于192mg/L开始升高是肺炎早期诊断的标志物（敏感性80.6%；特异性80.8%）。
SBCT后第3天开始每日测量CRP可能有助于SBCT并发肺炎的早期诊断。
