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科隆欧洲临床微生物与感染病学会卓越中心:侵袭性真菌感染外部咨询服务的两年分析

The Cologne ECMM Excellence Center: A Two-Year Analysis of External Consultation Service for Invasive Fungal Infections.

作者信息

Salmanton-García Jon, Koehler Philipp, Grothe Jan-Hendrik, Mellinghoff Sibylle C, Sal Ertan, Simon Michaela, Stemler Jannik, Cornely Oliver A, Sprute Rosanne

机构信息

Faculty of Medicine and University Hospital Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Herderstraße 52, 50931, Cologne, Germany.

Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, Excellence Center for Medical Mycology, University of Cologne, Cologne, Germany.

出版信息

Mycopathologia. 2024 Mar 11;189(2):25. doi: 10.1007/s11046-023-00822-1.

DOI:10.1007/s11046-023-00822-1
PMID:38466469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10927858/
Abstract

The European Confederation of Medical Mycology (ECMM), formed due to the surge in invasive fungal infections (IFI), initiated the Excellence Centers program in 2016 to guide stakeholders to leading medical mycology sites. This report focuses on the Cologne ECMM Excellence Center, recognized with Diamond status for active global involvement in 2017. The center offers free consultation via email and phone, responding within 24 h for life-threatening IFI, collecting data on origin, pathogens, infection details, and more. Over two years, 189 requests were received globally, predominantly from Germany (85%), mainly involving Aspergillus spp., Mucorales, and Candida spp. Fungal mixed infections occurred in 4% of cases. The center's service effectively addresses IFI challenges, advocating for a comprehensive study encompassing all ECMM Excellence Centers to enhance global mycological care. Proactive expansion of consultancy platforms is crucial, with future analyses needed to assess expert advice's impact on patient outcomes.

摘要

欧洲医学真菌学联合会(ECMM)因侵袭性真菌感染(IFI)激增而成立,于2016年启动卓越中心计划,以引导利益相关者前往领先的医学真菌学机构。本报告重点介绍科隆ECMM卓越中心,该中心在2017年因积极参与全球事务而获得钻石地位认可。该中心通过电子邮件和电话提供免费咨询,对于危及生命的IFI在24小时内做出回应,收集有关感染源、病原体、感染细节等数据。在两年多的时间里,全球共收到189份咨询请求,主要来自德国(85%),主要涉及曲霉属、毛霉目和念珠菌属。4%的病例发生了真菌混合感染。该中心的服务有效应对了IFI挑战,倡导开展一项涵盖所有ECMM卓越中心的综合研究,以加强全球真菌学护理。积极扩展咨询平台至关重要,未来需要进行分析,以评估专家建议对患者预后的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab32/10927858/f96b74036d50/11046_2023_822_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab32/10927858/f96b74036d50/11046_2023_822_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab32/10927858/f96b74036d50/11046_2023_822_Fig1a_HTML.jpg

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Mycopathologia. 2024 Jan 24;189(1):15. doi: 10.1007/s11046-024-00830-9.
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Unveiling the Hungarian landscape of laboratory and clinical management capacities for invasive fungal infections: navigating the frontlines against fungal menaces.揭示匈牙利侵袭性真菌感染的实验室和临床管理能力现状:应对真菌威胁的前沿探索。
Ther Adv Infect Dis. 2023 Dec 18;10:20499361231219315. doi: 10.1177/20499361231219315. eCollection 2023 Jan-Dec.
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Laboratory and clinical management capacity for invasive fungal infections: the Italian landscape.
实验室和侵袭性真菌感染临床管理能力:意大利现状。
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The Austrian landscape of diagnostic capacity and access to treatment for invasive fungal infections.奥地利的侵袭性真菌感染诊断能力和治疗机会的全景。
Mycoses. 2023 Dec;66(12):1056-1063. doi: 10.1111/myc.13650. Epub 2023 Aug 17.
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The Argentinian landscape of mycological diagnostic capacity and treatment accessibility.阿根廷的真菌学诊断能力和治疗可及性状况。
Med Mycol. 2023 Jun 5;61(6). doi: 10.1093/mmy/myad058.
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Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO).血液恶性肿瘤患者侵袭性真菌病的一级预防:德国血液学和肿瘤内科学会(DGHO)传染病工作组(AGIHO)的建议 2022 年更新版。
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