Palanisamy Jayasudha, Rajagopal Rajakrishnan, Alfarhan Ahmed
Department of Chemistry, Subramanya College of Arts and Science, Palani, Tamilnadu, 624618, India.
Department of Botany & Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
J Fluoresc. 2025 Apr;35(4):1969-1978. doi: 10.1007/s10895-024-03620-0. Epub 2024 Mar 11.
A benzoxazole-coumarin-based probe BOC, was synthesized and validated for its anion sensing ability and found to be effective in recognizing cyanide ions. Upon addition of cyanide, a spontaneous color change was observed that was visible to the naked eye. The sensitization process takes place with nucleophilic addition, and the cyanide ion added to the probe disrupts the intra molecular charge transfer transition (ICT) between the donor and acceptor units, causing the pink colored probe to become yellow. Ultraviolet and fluorescence methods were applied to measure the detection limits of probes with added cyanide ions, which were found to be 3.47 µM and 2.48 nM. The stoichiometry of the probe with the cyanide ion was determined by the Job's method, NMR titration, and mass spectrometry and was found to be in a 1:1 ratio. The results obtained from the visual and UV-visible spectral studies are justified by theoretical calculations. The cyanide-loaded probe induced visual changes, which enabled the development of a test strip for field application, and the prepared strip can be used to detect the ppm level of cyanide in water samples. The developed probe, BOC, can be used to detect cyanide ions in various water samples.
合成了一种基于苯并恶唑 - 香豆素的探针BOC，并对其阴离子传感能力进行了验证，发现它在识别氰离子方面有效。加入氰化物后，观察到肉眼可见的自发颜色变化。敏化过程通过亲核加成发生，添加到探针中的氰离子破坏了供体和受体单元之间的分子内电荷转移跃迁（ICT），导致粉红色的探针变为黄色。应用紫外和荧光方法测量添加氰离子的探针的检测限，发现分别为3.47 μM和2.48 nM。通过乔布氏法、核磁共振滴定和质谱法确定了探针与氰离子的化学计量比，发现为1:1。从视觉和紫外可见光谱研究获得的结果通过理论计算得到了验证。负载氰化物的探针引起了视觉变化，这使得能够开发用于现场应用的测试条，并且制备的试纸条可用于检测水样中ppm级的氰化物。所开发的探针BOC可用于检测各种水样中的氰离子。
