Programa de Pós-Graduação em Psiquiatria e Ciências do Comportamento, Departamento de Psiquiatria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Centro de Pesquisa em Álcool e Drogas, Hospital de Clínicas de Porto Alegre, UFRGS, Porto Alegre, RS, Brazil.
Programa de Pós-Graduação em Psiquiatria e Ciências do Comportamento, Departamento de Psiquiatria, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Centro de Pesquisa em Álcool e Drogas, Hospital de Clínicas de Porto Alegre, UFRGS, Porto Alegre, RS, Brazil. School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, United Kingdom.
Braz J Psychiatry. 2024;46:e20233265. doi: 10.47626/1516-4446-2023-3265. Epub 2024 Mar 6.
This study investigated the relationship between impulsivity and early trauma through a network analysis in individuals diagnosed with different substance use disorders.
In a cross-sectional design, the sample included 556 men with substance use disorders (195 with alcohol use, 157 with cocaine/crack use, and 214 with polysubstance use). Early trauma and impulsive behavior were assessed using the Childhood Trauma Questionnaire and the Barratt Impulsiveness Scale, respectively. The connection between trauma and impulsivity was assessed using network analysis through a fused graphical lasso algorithm.
No connection was observed between impulsivity and trauma networks in individuals with alcohol use disorder. In those with cocaine use disorder, networks were linked through the motor domain and sexual abuse nodes. Inverse connections were observed between the emotional neglect node and perseverance, but not the non-planning node. In polysubstance use, the connection between impulsivity and trauma networks was weak, with the cognitive complexity node connecting to the trauma network through physical abuse. There connections were inversely proportional between the motor domain and emotional neglect nodes, as well as between cognitive instability and physical neglect.
Our results suggest that the relationship between the type of early (childhood) trauma and the expression of impulsivity could lead to different substance use profiles.
本研究通过对不同物质使用障碍个体进行网络分析，探讨冲动性与早期创伤之间的关系。
采用横断面设计，样本包括 556 名男性物质使用障碍患者（195 名酒精使用障碍患者、157 名可卡因/快克使用障碍患者和 214 名多物质使用障碍患者）。采用儿童期创伤问卷和巴瑞特冲动量表分别评估早期创伤和冲动行为。通过融合图形套索算法的网络分析评估创伤和冲动之间的联系。
酒精使用障碍患者的冲动性和创伤性网络之间没有联系。可卡因使用障碍患者的网络通过运动域和性虐待节点连接。情感忽视节点与坚毅之间存在反向连接，但与非计划节点没有连接。在多物质使用中，冲动性和创伤性网络之间的连接较弱，认知复杂性节点通过身体虐待与创伤性网络连接。运动域和情感忽视节点之间，以及认知不稳定性和身体忽视之间存在反向连接。
我们的结果表明，早期（儿童期）创伤类型与冲动表达之间的关系可能导致不同的物质使用模式。
